Tuesday, March 18, 2008

MAD COW DISEASE typical vs atypical terminology

Sunday, March 16, 2008

MAD COW DISEASE terminology UK c-BSE (typical), atypical BSE H or L, and or Italian L-BASE

Greetings,

I thought i might try and sort things out about this a bit. Some folks seem to be a bit confused,(confusious included has been confused a time or two to be sure). but i think some clarification needs to be done. you can interpret it the way you want. i have my opinions on why i interpret the science one way, you may have yours. here goes ;

WE first heard of the atypical called BASE Bovine Amyloidotic Spongiform Encephalopathy (Italy), and it was said then that the molecular signature of this previously undescribed bovine PrPSc was similar to that encountered in a distinct subtype of sporadic Creutzfeldt-Jakob disease. The Italian BASE Bovine Amyloidotic Spongiform Encephalopathy termed that due to the 'amyloid plaques'.

THIS is where i start to have problems with the term. if you will recall, the first ten nvCJD in young adolescents, 'amyloid plaques' were used then to differentiate between the sporadic CJDs and nvCJD, UNTIL the 'amyloid plaques' stared showing up in some sporadic CJDs. now (10%) amyloid deposits, called prion protein (PrP) amyloid plaques, may be observed in sporadic CJD.

ALSO, with the BASE, you will find that some want to hypothesize that the BASE is just BSE in older cattle.

well, if that was the case, then would not sporadic CJD be just nvCJD in old people?

ALSO, it was said that nvCJD was only in the young. this too was part of a diagnostic criteria to differentiate between the nvCJD and sporadic CJDs, until sCJD started showing up in young adolescents.

ALSO, it was said that only the nvCJD have long incubation period, this too was part of diagnostic criteria to differentiate between the nvCJD and sporadic CJDs, until the long incubation started showing up in some sporadic CJDs.

ALSO, it was said that on the nvCJD victims had psychological mental symptoms, not the sporadic CJDs, that too until the psychological and mental symptoms started showing up in some of the sporadic CJDs.

FOR these reasons, I cannot accept that the difference in bands and mass (heavier or lighter), are the meaning of another different strain differentiating between UK c-BSE (typical), atypical BSE H or L, and or Italian L-BASE.

I think i might be partly to blame for the confusion, because sometimes i will use BASE, and sometimes i will use atypical BSE, h or l. same with the nvCJD, i still catch myself using that term, as opposed to the newest terminology of vCJD.

kind regards,
terry

SEE FULL TEXT WITH SOURCES


Sunday, March 16, 2008

MAD COW DISEASE terminology UK c-BSE (typical), atypical BSE H or L, and or Italian L-BASE

http://bse-atypical.blogspot.com/2008/03/mad-cow-disease-terminology-uk-c-bse.html


TSS

Thursday, March 13, 2008

DOWNER COW BLUES SENATORS WANT CRACKDOWN

DOWNER COW BLUES SENATORS WANT CRACKDOWN


Senators want crackdown on violations of downer cow prohibitions

Last Update: 5:12 pm


WASHINGTON (AP) - Senators Dianne Feinstein and Barbara Boxer of California have introduced a bill to stiffen penalties against slaughterhouses that illegally process cows too sick to stand.

The legislation comes in response to the scandal over a Southern California slaughterhouse that improperly allowed so-called downer cattle into the food supply, leading to a recall of 143 million pounds of beef. Downer cows pose higher risk of mad cow disease and other infections.

The bill would let the Agriculture Department impose a fine for a first violation, a one-year suspension for a second violation and permanent shutdown for a third violation.

The legislation is also sponsored by Senators Ted Stevens of Alaska and Daniel Akaka of Hawaii.


http://www.fox6.com/news/state/story.aspx?content_id=ae9882e6-db32-485e-9c95-9adc899e9998




Panel grills meatpacking chief on beef recall at Chino plant

J. Scott Applewhite / Associated Press

Westland/Hallmark Meat Co. President Steve Mendell, center, prepares to testify before a House subcommittee hearing on federal regulations for food and food safety.

Steve Mendell of closed Westland/ Hallmark company tells lawmakers, 'My system broke down.'

By Nicole Gaouette, Los Angeles Times Staff Writer

March 13, 2008

WASHINGTON -- The president of the Chino meatpacking plant that triggered the largest beef recall in U.S. history admitted Wednesday that crippled cows, which are more likely to carry disease, probably entered the food supply at his company.

"Obviously my system broke down," said Steve Mendell, president of Westland/Hallmark Meat Co., once a major supplier to the school lunch program.

Mendell initially told a House oversight subcommittee that "downer" cows at his plant "were not slaughtered, ground or sold."

But after lawmakers screened a graphic undercover video that showed ailing cows being jabbed with electric prods, beaten and rolled with forklifts toward slaughter, Mendell acknowledged that the four-minute clip did indeed show that at least two cows were processed into food.

Dressed soberly in black, Mendell, of Newport Beach, was flushed but composed, apologetic and insistent that the meat at his plant was safe for consumption. He told lawmakers that he had received death threats, that his family and employees had suffered, and that his company "is ruined" and would not reopen.

"My whole life is up in smoke," he said.

After watching a video of his plant taken by an undercover investigator from the Humane Society of the United States, Mendell briefly bowed his head and shut his eyes.

"Would you consume meat from a cow slaughtered that way?" asked Rep. Janice Schakowsky (D-Ill.).

"No," Mendell said.

The hearing by a House Energy and Commerce subcommittee touched on multiple failures in the nation's food safety system, not only within Mendell's firm but also by independent auditors, the Food and Drug Administration and the U.S. Department of Agriculture's on-site investigators responsible for monitoring Westland/Hallmark.

"There is a serious problem with our food safety system," said Rep. Bart Stupak (D-Mich.), chairman of the Oversight and Investigations Subcommittee.

Stupak noted that since his subcommittee began investigating the FDA's ability to protect the nation's food supply 14 months ago there have been at least 163 recalls and health alerts tied to FDA-regulated products. Since 2007, Stupak added, there have been 67 meat recalls totaling about 180 million pounds.

Practices at the Westland/Hallmark plant led the USDA to announce the recall of 143 million pounds of meat, 50 million of which had been sent to school lunch programs. About 20 million pounds of the school-bound meat has already been consumed.

Mendell, who ignored an initial summons to appear before the committee in February, was issued a subpoena to appear Wednesday. He arrived with one of Washington's most high-profile lawyers, Asa Hutchinson, a former congressman and former member of the Bush administration whom Mendell hired Friday.

Democrats and Republicans, who have spent most of this Congress bickering with each other, ganged up on the Westland/Hallmark president.

"There's an easy way and a hard way to answer questions from this committee," Rep. John D. Dingell (D-Mich.) warned Mendell. "Either way, we'll find out what we want to know."

Rep. Joe L. Barton (R-Texas) added his own word of caution: "There's no daylight between Republicans and Democrats on this issue."

Action against Westland/Hallmark began when the Humane Society released video filmed by an investigator Jan. 30. Five on-site USDA inspectors had failed to notice anything wrong.

The plant, which slaughtered about 500 cattle a day, shut operations Feb. 4. After the Humane Society provided video evidence that downer cows were being slaughtered, Westland/Hallmark voluntarily recalled the beef Feb. 17.

Downer cows have been banned from entering the food supply since 2004, but the USDA has made an exception for cows that were inspected after they fell and seemed only to have external injuries. The Westland/Hallmark cows were not being inspected.

Page 2 of 2

Ailing cows are at greater risk of carrying E. coli, salmonella bacteria and bovine spongiform encephalopathy, a fatal neurological disorder known as mad cow disease.

Rep. Edward Whitfield (R-Ky.) grimaced as he watched the video, which at one point showed a downer cow being "waterboarded" by a worker who directed a hose of water into the animal's nostrils. Whitfield suggested to Mendell that the USDA should ban the slaughter of any downer cows. But Mendell contended that those situations should be judged on a case-by-case basis and pointed out that companies lost money on any cow that was euthanized.

Mendell told lawmakers that he wished he had installed cameras in the plant after a 2005 citation for inhumane treatment of animals. Instead, he said, he improved training, instituting monthly sessions of about an hour to an hour and a half.

Rep. Michael C. Burgess (R-Texas), who noticed Spanish-speaking workers in the video, asked whether Mendell might have had a language problem, but Mendell responded that the supervisors were bilingual.

Mendell produced records that showed that the Humane Society investigator was trained. But in an interview, Humane Society President Wayne Pacelle said the investigator never received training. Pacelle said the Humane Society would not reveal the identity of the investigator because he would continue to do similar work, but described him as a committed vegan.

Mendell pointed to 17 external audits and a dozen internal ones last year that showed his plant's practices were exemplary, but lawmakers were unimpressed.

"So many audits, what went wrong?" countered Rep. John Shimkus (R-Ill.). "There's something wrong in all these reviews, there's something wrong . . . in the corporate culture. We have to figure out why you had so many reviews, and then the Humane Society does its undercover, and voila."

Even if downer cows had been slaughtered, Mendell stressed, the processed meat would still be all right as later inspections screened out any "specified risk materials" that might lead to mad cow disease.

"There's less than a minute chance of that material being contaminated," he said.

Rep. Gene Green (D-Texas) told Mendell that there were children in his district who had consumed Westland/Hallmark meat. He noted that it could take more than a decade before mad cow disease is detected in humans.

"In 13 years, you're not going to be around," Green said. "That's my concern and the concern of this Congress."

nicole.gaouette@latimes.com



http://www.latimes.com/business/la-na-hallmark13mar13,1,5872989.story



http://www.latimes.com/business/la-na-hallmark13mar13,0,4930134.story?page=2&track=ntothtml



tip of the iceberg.

what went wrong ???

they call it, kaaching $$$

Web posted Wednesday, February 18, 1998 2:02 p.m. CT

Graphic pictures greet Winfrey jury

By KAY LEDBETTER Globe-News Farm and Ranch Editor

Pictures of sheep heads, euthanized pets and roadkill greeted jurors this morning as they returned to the continuation of the cattlemen vs. Oprah Winfrey lawsuit.

The lawsuit continues today in U.S. District Mary Lou Robinson's court, but in a much diminished state.

snip...

Defense lawyer Charles Babcock called Van Smith, a City Paper reporter from Baltimore who had written an article on rendering plants in September 1995.

Smith and Babcock went through more than 50 pictures taken as the reporter toured the Valley Proteins plant in Baltimore and followed a rendering truck to the local animal shelter, a sausage plant and a slaughterhouse.

The pictures showed offal being emptied from the slaughterhouses. They showed animal shelter workers in the euthanasia room; barrels of dead animals in a refrigerated room at the animal shelter; waste meat from the sausage plant; and dead sheep from the slaughterhouse.

Web posted Friday, January 23, 1998 5:49 a.m. CT

TSS

Witness testifies some ill cattle sent to rendering plant

By CHIP CHANDLER Globe-News Staff Writer

snip...

Mike Engler -- son of Paul Engler, the original plaintiff and owner of Cactus Feeders Inc. -- agreed that more than 10 cows with some sort of central nervous system disorder were sent to Hereford By-Products.

The younger Engler, who has a doctorate in biochemistry from Johns Hopkins University, was the only witness jurors heard Thursday in the Oprah Winfrey defamation trial. His testimony will resume this morning.

According to a U.S. Department of Agriculture report from which Winfrey attorney Charles Babcock quoted, encephalitis caused by unknown reasons could be a warning sign for bovine spongiform encephalopathy, or mad cow disease.

Encephalitis was indicated on the death certificates -- or ``dead slips'' -- of three Cactus Feeders cows discussed in court. The slips then were stamped, ``Picked up by your local used cattle dealer'' before the carcasses were taken to the rendering plant.

snip...

http://www.amarillonet.com/


USDA CERTIFIED NON-AMBULATORY DOWNER COW SCHOOL LUNCH PROGRAM


http://downercattle.blogspot.com/2008/02/beef-recall-nationwide-school-lunch.html


Specified Risk Material SRM

On January 18, 2002, FDA's New Orleans District Office issued a Warning Letter to J. Randall Mayes, Pulaski, Tennessee, a dairy farmer. An FDA inspection conducted November 26 28, 2001, confirmed that the farmer sold a cow for use as human food containing gentamicin residues. USDA analysis of tissue samples from the cow sold by Mayes identified the presence of 7.12 ppm of gentamicin in the kidney tissue. There is no established tolerance for gentamicin in cattle. In addition, FDA's investigation found that the dairy farmer held animals under conditions which were so inadequate that diseased animals and/or medicated animals bearing potentially harmful drug residues were likely to enter the food supply.


http://www.fda.gov/ora/about/enf_story/archive/2002/ch5/cvm1.htm


The Warning Letter also noted that the owner holds animals under conditions which are so inadequate that diseased animals and/or medicated animals bearing potentially harmful drug residues are likely to enter the food supply.


http://www.fda.gov/ora/about/enf_story/archive/2001/ch5/default.htm


Mr. Sturm was found to hold animals on his farm under conditions that are so inadequate that diseased animals and/or medicated animals bearing potentially harmful drug residues are likely to enter the food supply. In addition, he failed to use the drug, Albon, containing sulfadimethoxine, in conformance with the labeling.

A warning letter was issued to the following firms for violations related to 21 CFR Part 589.2000-Animal Proteins Prohibited in Ruminant Feed. This regulation is intended to prevent the establishment and amplification of Bovine Spongiform Encephalopathy (BSE).

. Scott Nelson, Owner, Integra Fish Foods, Inc., Grand Junction, CO

. Bruce A. Burgett, General Manager, The Carrollton Farmers Exchange, Carrollton, OH

Violations included failure to label feeds that contain, or may contain, prohibited materials with the required cautionary statement "Do Not Feed to Cattle or Other Ruminants," insufficient customer records to track the distribution of products, and lack of written procedures for cleaning or flushing equipment after mixing feeds containing prohibited material.

http://www.fda.gov/cvm/Sep_Oct01.htm

Mr. Van Dam was found to hold animals under improper conditions whereby diseased animals and/or medicated animals bearing potentially harmful drug residues are likely to enter the food supply.

Ms. Silveira was found to be adulterating the drug Mutual Pharmaceutical brand of sulfamethoxazole and trimethoprim tablets, since she did not follow her veterinarian's prescribed withdrawal time of thirty days prior to slaughter.

Mr. Edwards did not properly identify treated animals to assure they are not sold for slaughter, did not maintain treatment records, and he did not follow labeling directions for medicated feed.

O & L Dairy was found to lack an adequate system for determining the medication status of animals offered for slaughter, and for assuring that animals which had been medicated had been withheld from slaughter for the appropriate periods of time to deplete potentially hazardous residues of drugs.

Mr. Sturm was found to hold animals on his farm under conditions that are so inadequate that diseased animals and/or medicated animals bearing potentially harmful drug residues are likely to enter the food supply. In addition, he failed to use the drug, Albon, containing sulfadimethoxine, in conformance with the labeling.

A warning letter was issued to the following firms for violations related to 21 CFR Part 589.2000-Animal Proteins Prohibited in Ruminant Feed. This regulation is intended to prevent the establishment and amplification of Bovine Spongiform Encephalopathy (BSE).

. Scott Nelson, Owner, Integra Fish Foods, Inc., Grand Junction, CO

. Bruce A. Burgett, General Manager, The Carrollton Farmers Exchange, Carrollton, OH

Violations included failure to label feeds that contain, or may contain, prohibited materials with the required cautionary statement "Do Not Feed to Cattle or Other Ruminants," insufficient customer records to track the distribution of products, and lack of written procedures for cleaning or flushing equipment after mixing feeds containing prohibited material.

http://www.fda.gov/cvm/Sep_Oct.htm

Our investigation also found that you hold animals on your farm under conditions that are so inadequate that diseased animals and/or medicated animals bearing potentially harmful drug residues are likely to enter the food supply. For example, you failed to maintain treatment records for bull calves fed medicated milk replacer, lack a system for assuring that the milk replacer is used in a manner not contrary to label instructions, and lack a system for assuring the medicated animals have been withheld from slaughter for appropriate periods of time to permit depletion of potentially hazardous drug residues from edible tissues. Foods from animals held under such conditions are adulterated under Section 402(a)(4) of the Act [21 U.S.C. Section 342(a)(4)].

http://www.fda.gov/foi/warning_letters/archive/awl2.htm


Our investigation also found that you hold animals on your farm under conditions that are so inadequate that diseased animals and lormedicated animals bearing potentially harmful drug residues are likely to enter the food supply. For example, you lack a system for assuring that drugs are used in a manner not contrary to label instructions, and for assuring animals medicated on your farrn have been withheld from slaughter for appropriate periods of time to permit depletion of potentially hazardous drug residues from edible tissues. Foods from animals held under such conditions are adulterated under Section 402(a)(4) of the Act.

http://www.fda.gov/foi/warning_letters/archive/awl6.htm


Our investigation also found that you hold animals which are ultimately offered for slaughter as food, under conditions which are so inadequate that diseased animals and/or medicated animals bearing potentially harmful drug residues are likely to enter the food supply.

John Weststeyn 2 T & J Dairy

http://www.fda.gov/foi/warning_letters/archive/awl130.pdf


FOR IMMEDIATE RELEASE Statement May 4, 2004 Media Inquiries: 301-827-6242 Consumer Inquiries: 888-INFO-FDA

Statement on Texas Cow With Central Nervous System Symptoms On Friday, April 30 th , the Food and Drug Administration learned that a cow with central nervous system symptoms had been killed and shipped to a processor for rendering into animal protein for use in animal feed.

FDA, which is responsible for the safety of animal feed, immediately began an investigation. On Friday and throughout the weekend, FDA investigators inspected the slaughterhouse, the rendering facility, the farm where the animal came from, and the processor that initially received the cow from the slaughterhouse.

FDA's investigation showed that the animal in question had already been rendered into "meat and bone meal" (a type of protein animal feed). Over the weekend FDA was able to track down all the implicated material. That material is being held by the firm, which is cooperating fully with FDA.

Cattle with central nervous system symptoms are of particular interest because cattle with bovine spongiform encephalopathy or BSE, also known as "mad cow disease," can exhibit such symptoms. In this case, there is no way now to test for BSE. But even if the cow had BSE, FDA's animal feed rule would prohibit the feeding of its rendered protein to other ruminant animals (e.g., cows, goats, sheep, bison).

FDA is sending a letter to the firm summarizing its findings and informing the firm that FDA will not object to use of this material in swine feed only. If it is not used in swine feed, this material will be destroyed. Pigs have been shown not to be susceptible to BSE. If the firm agrees to use the material for swine feed only, FDA will track the material all the way through the supply chain from the processor to the farm to ensure that the feed is properly monitored and used only as feed for pigs.


http://www.fda.gov/bbs/topics/news/2004/NEW01061.html


10,000,000+ LBS. of PROHIBITED BANNED MAD COW FEED I.E. MBM IN COMMERCE USA 2007

Date: March 21, 2007 at 2:27 pm PST

RECALLS AND FIELD CORRECTIONS: VETERINARY MEDICINES -- CLASS II

___________________________________

PRODUCT

Bulk cattle feed made with recalled Darling's 85% Blood Meal, Flash Dried, Recall # V-024-2007

CODE

Cattle feed delivered between 01/12/2007 and 01/26/2007

RECALLING FIRM/MANUFACTURER

Pfeiffer, Arno, Inc, Greenbush, WI. by conversation on February 5, 2007.

Firm initiated recall is ongoing.

REASON

Blood meal used to make cattle feed was recalled because it was cross-contaminated with prohibited bovine meat and bone meal that had been manufactured on common equipment and labeling did not bear cautionary BSE statement.

VOLUME OF PRODUCT IN COMMERCE

42,090 lbs.

DISTRIBUTION

WI

___________________________________

PRODUCT

Custom dairy premix products: MNM ALL PURPOSE Pellet, HILLSIDE/CDL Prot-Buffer Meal, LEE, M.-CLOSE UP PX Pellet, HIGH DESERT/ GHC LACT Meal, TATARKA, M CUST PROT Meal, SUNRIDGE/CDL PROTEIN Blend, LOURENZO, K PVM DAIRY Meal, DOUBLE B DAIRY/GHC LAC Mineral, WEST PIONT/GHC CLOSEUP Mineral, WEST POINT/GHC LACT Meal, JENKS, J/COMPASS PROTEIN Meal, COPPINI - 8# SPECIAL DAIRY Mix, GULICK, L-LACT Meal (Bulk), TRIPLE J - PROTEIN/LACTATION, ROCK CREEK/GHC MILK Mineral, BETTENCOURT/GHC S.SIDE MK-MN, BETTENCOURT #1/GHC MILK MINR, V&C DAIRY/GHC LACT Meal, VEENSTRA, F/GHC LACT Meal, SMUTNY, A-BYPASS ML W/SMARTA, Recall # V-025-2007

CODE

The firm does not utilize a code - only shipping documentation with commodity and weights identified.

RECALLING FIRM/MANUFACTURER

Rangen, Inc, Buhl, ID, by letters on February 13 and 14, 2007. Firm initiated recall is complete.

REASON

Products manufactured from bulk feed containing blood meal that was cross contaminated with prohibited meat and bone meal and the labeling did not bear cautionary BSE statement.

VOLUME OF PRODUCT IN COMMERCE

9,997,976 lbs.

DISTRIBUTION

ID and NV

END OF ENFORCEMENT REPORT FOR MARCH 21, 2007





http://www.fda.gov/Safety/Recalls/EnforcementReports/2007/ucm120446.htm





Subject: MAD COW FEED RECALL USA SEPT 6, 2006 1961.72 TONS IN COMMERCE AL, TN, AND WV

Date: September 6, 2006 at 7:58 am PST

PRODUCT

a) EVSRC Custom dairy feed, Recall # V-130-6;

snip...

PLEASE SEE FULL TEXT AND LONG LAUNDRY LIST OF MAD COW PROTEIN AND SRM ''IN COMMERCE'' ;

snip...

(PLEASE NOTE, .005 grams of TSE tainted mad cow feed is lethal enough to kill a cow. ...tss)

SEE SRMS


http://madcowspontaneousnot.blogspot.com/2008/02/specified-risk-materials-srm.html



USDA CERTIFIED H-BASE MAD COW SCHOOL LUNCH PROGRAM


http://cjdmadcowbaseoct2007.blogspot.com/2008/02/usda-certified-h-base-mad-cow-school.html



Sunday, February 17, 2008

Release No. 0046.08 Statement by Secretary of Agriculture Ed Schafer Regarding Hallmark/Westland Meat Packing Company Two Year Product Recall

Release No. 0046.08

Contact:

USDA Press Office (202) 720-4623


http://cjdmadcowbaseoct2007.blogspot.com/2008/02/release-no-004608-statement-by.html


Thursday, February 21, 2008

TRANSCRIPT: Technical Briefing - Hallmark/Westland Meat Packing Company - (02/21/08)

Release No. 0054.08


http://downercattle.blogspot.com/


http://downercattle.blogspot.com/2008/02/transcript-technical-briefing.html


Geographical BSE Risk (GBR) assessments covering 2000-2006

Date : 01.08.2006


http://www.efsa.europa.eu/EFSA/Scientific_Document/GBR_assessments_table_Overview_assessed_countries_2002-2006.pdf


In this context, a word is in order about the US testing program. After the discovery of the first (imported) cow in 2003, the magnitude of testing was much increased, reaching a level of >400,000 tests in 2005 (Figure 4). Neither of the 2 more recently indigenously infected older animals with nonspecific clinical features would have been detected without such testing, and neither would have been identified as atypical without confirmatory Western blots. Despite these facts, surveillance has now been decimated to 40,000 annual tests (USDA news release no. 0255.06, July 20, 2006) and invites the accusation that the United States will never know the true status of its involvement with BSE.


http://www.cdc.gov/ncidod/EID/vol12no12/06-0965.htm


From: Terry S. Singeltary Sr. [flounder9@verizon.net] Sent: Thursday, September 08, 2005 6:17 PM To: fsis.regulationscomments@fsis.usda.gov

Subject: [Docket No. 03-025IFA] FSIS Prohibition of the Use of Specified Risk Materials for Human Food and Requirements for the Disposition of Non-Ambulatory Disabled Cattle

Greetings FSIS,

I would kindly like to submit the following to [Docket No. 03-025IFA] FSIS Prohibition of the Use of Specified Risk Materials for Human Food and Requirements for the Disposition of Non-Ambulatory Disabled Cattle

THE BSE/TSE SUB CLINICAL

Non-Ambulatory Disabled Cattle Broken bones and such may be the first signs of a sub clinical BSE/TSE Non-Ambulatory Disabled Cattle ;

SUB CLINICAL PRION INFECTION MRC-43-00 Issued: Monday, 28 August 2000

NEW EVIDENCE OF SUB-CLINICAL PRION INFECTION: IMPORTANT RESEARCH FINDINGS RELEVANT TO CJD AND BSE

A team of researchers led by Professor John Collinge at the Medical Research Council Prion Unit1 report today in the Proceedings of the National Academy of Sciences, on new evidence for the existence of a sub-clinical form of BSE in mice which was unknown until now. The scientists took a closer look at what is known as the species barrier - the main protective factor which limits the ability of prions2 to jump from one species to infect another. They found the mice had a sub-clinical form of disease where they carried high levels of infectivity but did not develop the clinical disease during their normal lifespan. The idea that individuals can carry a disease and show no clinical symptoms is not new. It is commonly seen in conventional infectious diseases. Researchers tried to infect laboratory mice with hamster prions3 called Sc237 and found that the mice showed no apparent signs of disease. However, on closer inspection they found that the mice had high levels of mouse prions in their brains. This was surprising because it has always been assumed that hamster prions could not cause the disease in mice, even when injected directly into the brain. In addition the researchers showed that this new sub-clinical infection could be easily passed on when injected into healthy mice and hamsters. The height of the species barrier varies widely between different combinations of animals and also varies with the type or strain of prions. While some barriers are quite small (for instance BSE easily infects mice), other combinations of strain and species show a seemingly impenetrable barrier. Traditionally, the particular barrier studied here was assumed to be robust. Professor John Collinge said: "These results have a number of important implications. They suggest that we should re-think how we measure species barriers in the laboratory, and that we should not assume that just because one species appears resistant to a strain of prions they have been exposed to, that they do not silently carry the infection.

This research raises the possibility, which has been mentioned before, that apparently healthy cattle could harbour, but never show signs of, BSE. "This is a timely and unexpected result, increasing what we know about prion disease. These new findings have important implications for those researching prion disease, those responsible for preventing infected material getting into the food chain and for those considering how best to safeguard health and reduce the risk that theoretically, prion disease could be contracted through medical and surgical procedures."

ISSUED FRIDAY 25 AUGUST UNDER EMBARGO. PLEASE NOTE THAT THE EMBARGO IS SET BY THE JOURNAL.


http://www.mrc.ac.uk/index/public_interest/public-press_office/public-press_releases_2000/public-mrc-43-00.htm


full text ;

9/13/2005


http://www.fsis.usda.gov/OPPDE/Comments/03-025IFA/03-025IFA-2.pdf


[Docket No. FSIS-2006-0011] FSIS Harvard Risk Assessment of Bovine Spongiform Encephalopathy (BSE)


http://www.fsis.usda.gov/OPPDE/Comments/2006-0011/2006-0011-1.pdf


SCHOOL LUNCH PROGRAM FROM DOWNER CATTLE UPDATE


http://downercattle.blogspot.com/



Beef - Westland/Hallmark Recall OF BEEF WITH DEADSTOCK DOWNER COWS, THE MOST HIGH RISK CATTLE FOR BSE/TSE AKA MAD COW DISEASE


Additional Products Listing 5-20-08



http://www.cdph.ca.gov/pubsforms/Documents/fdb%20eru%20Hmrk%20Addl%20Prod052008.pdf




http://www.cdph.ca.gov/HEALTHINFO/Pages/FDB%20Beef-WestlandHallmarkRecall.aspx



TOTAL DISTRIBUTION LIST



http://www.cdph.ca.gov/pubsforms/Documents/fdb%20eru%20Hmrk%20All%20Dist042008.pdf



ADDITIONAL PRODUCTS CONTAINING RECALLED BEEF



http://www.cdph.ca.gov/pubsforms/Documents/fdb%20eru%20Hmrk%20Addl%20Prod052008.pdf




SEE FULL LIST OF ALL RECALLED SUSPECT DEAD STOCK DOWNER COW PRODUCTS HERE ;



http://www.cdph.ca.gov/HEALTHINFO/Pages/FDB%20Beef-WestlandHallmarkRecall.aspx




>>>In the papers, the government alleges the meatpacking plant slaughtered and processed downer cows for nearly four years — from January 2004 to September 2007 — <<<



>> 95%) downer or dead dairy cattle and a few horses. Sheep had never been fed.





We believe that these findings may indicate the presence of a previously unrecognized scrapie-like disease in cattle and wish to alert dairy practitioners to this possibility.

snip...

PROCEEDINGS OF THE SEVENTH ANNUAL WESTERN CONFERENCE FOR FOOD ANIMAL VETERINARY MEDICINE, University of Arizona, March 17-19, 1986




http://web.archive.org/web/20030331063559/http://www.bseinquiry.gov.uk/files/mb/m09a/tab01.pdf






http://web.archive.org/web/20030516051623/http://www.bseinquiry.gov.uk/files/mb/m09/tab05.pdf





IN CONFIDENCE

PERCEPTIONS OF UNCONVENTIONAL SLOW VIRUS DISEASES OF ANIMALS IN THE USA




http://collections.europarchive.org/tna/20080102193705/http://www.bseinquiry.gov.uk/files/mb/m11b/tab01.pdf






http://downercattle.blogspot.com/2009/09/suit-meatpacker-used-downer-cows-for-4.html




"The alleged misrepresentations by Hallmark and Westland could have impacted the health of many of our nation’s most vulnerable citizens--our schoolchildren," said Tony West, Assistant Attorney General of the Justice Department’s Civil Division. "Our intervention in this case demonstrates how seriously we will pursue allegations such as these."



http://downercattle.blogspot.com/2009/05/us-government-sues-westlandhallmark.html





TSS

Monday, March 10, 2008

Mr. Will Hueston DVM on school lunch program, downers, and mad cow disease 2004 and 2008

Mr. Will Hueston DVM on school lunch program, downers, and mad cow disease 2004 and 2008



A Case of Abuse, Heightened

NYTimes

By JOE NOCERA

Published: March 8, 2008

snip...

Governments all over the world quickly took note and began instituting a series of measures to ensure that B.S.E.-infected cattle would not infiltrate the food supply. The United States, for instance, ordered stepped-up inspections to root out B.S.E., instituted import controls and mandated rules to ensure that cattle brains and spinal cords did not wind up being ingested by cows as part of their feed.

“The challenge to controlling B.S.E. is to control the feed,” Mr. Hueston said. Indeed, he says, many scientists believe that even infected cows can be safely eaten so long as their brains and spinal cord have been removed. But as a matter of course, those parts are removed from every cow, and on the very rare occasion when B.S.E. is diagnosed in a cow, it is destroyed. In truth, the story of mad cow disease has been a public health triumph.

As for downer cows, in the scheme of things they pose a far smaller risk factor for mad cow disease than, say, cattle feed. Still, the government doesn’t want to take any chances, so its rules state that cattle arriving at the slaughterhouse in a “nonambulatory” fashion must be euthanized and their meat must not enter the food supply. There is, however, one exception — an exception that drives Mr. Pacelle crazy. If a cow arrives at the slaughterhouse on its feet and passes inspection and then goes down, it can be still be slaughtered — so long as a U.S.D.A. veterinarian reinspects the animal. ...


http://www.nytimes.com/2008/03/08/business/08nocera.html



Will Hueston, DVM, director of the University of Minnesota's Center for Animal Health and Food Safety 2004 Mr. Hueston DVM claims ;

Senate wants to keep downed cattle out of food supply Robert Roos News Editor

Nov 10, 2003 (CIDRAP News) – In an effort to ensure that sick cattle are kept out of the food supply, the Senate last week approved a measure to bar the Department of Agriculture (USDA) from approving the use of "downed" animals for human consumption.

snip...

Cohen said nonambulatory cows can be approved for food use if they show no signs of illness, which can happen with injured animals. "A lot of them are older dairy cows that have either hip or leg injuries," he explained. "Sometimes they have accidental slips in transportation, and that's why a lot of our inspection takes place in the transport vehicle itself, so that the animal doesn't suffer when being moved."

Cohen couldn't say how many nonambulatory cattle turn up at slaughter plants each year or how many are used for food. The AP report said the USDA has estimated that 130,000 downed animals are slaughtered annually.

Akaka said it's not possible to distinguish BSE from many other diseases by simple inspection. "Consequently, BSE-infected cattle can be approved for human and animal consumption," he asserted.

Will Hueston, DVM, director of the University of Minnesota's Center for Animal Health and Food Safety in St. Paul, agreed that BSE has no unique clinical signs that make it easily recognizable. Consquently, he said, there is a theoretical risk that a BSE-infected cow could end up food, though no BSE cases have been seen in the United States. "If we had BSE, an animal that [had the disease and] was unable to move because of a broken leg and showed no signs of disease, no fever or abnormal behavior, could enter the food chain," Hueston said.

He added, "I wouldn't go too far down that line, though," because the USDA's surveillance program for BSE focuses largely on downed cattle, which are among the cattle at highest risk. In fiscal year 2003 (which ended Sep 30), the agency's Animal and Plant Health Inspection Service (APHIS) tested 20,277 cattle for BSE, including 16,560 downed cattle, according to information on the agency's Web site. The carcasses of tested animals are held until the test results are in.

In BSE-affected countries, high-risk tissues, including the brain and spinal cord, are removed from all adult cattle at the time of slaughter to guard against the risk of invisible BSE cases entering the food chain, Hueston noted. The abnormal prion proteins associated with BSE have not been found in muscle tissues used as meat.

Cattle that are condemned as unfit for human consumption are sent for rendering, in which the carcass is cooked to remove water and separate fat from protein, Hueston said. The fat and protein are used in pet food, feed for animals other than cattle or other ruminants, and various other products. As a precaution against BSE, material from ruminants cannot legally be fed to ruminants.

See also:

Sen. Akaka's news release


http://akaka.senate.gov/~akaka/releases/03/11/2003B06340.html



http://www.cidrapforum.org/cidrap/content/other/bse/news/nov1003cattle.html



Atlantic Monthly Article is on the Web

Atlantic Monthly article by Ellen Ruppel Shell on mad cow disease in USA

A few colorful quotes from a 13 page article: 'In fact, brain doesn't just enter our food chain but goes directly into the human food supply. Each year, according to the USDA's Food Safety and Inspection Service, which is charged with regulating the meat industry, about a million cow brains are sold for consumption in the United States, and others are exported. Generally these are whole brains taken from cows slaughtered in the kosher manner -- that is, their throats are cut while they are still conscious. Most cows in the United States, though, are shot in the head with a stun gun before having their throats cut, a process perhaps more humane but also, at least when a pneumatic stun gun that injects air is used, more likely to contaminate other parts of the carcass with brain. This pneumatic gun can crack the cow's skull, causing the brain to leak out. And the force of the gun is such that it can blow pieces of brain into the bloodstream, where they can be carried to the animal's lungs or liver. Tam Garland has recovered chunks of brain as large as six inches across in the lungs of slaughtered cattle. Canadian researchers have spotted pieces of brain about two and a half inches wide lodged in cow livers.'

'Will Hueston, a veterinary epidemiologist formerly with the USDA and now an associate dean at the Virginia-Maryland Regional College of Veterinary Medicine, says that the agency has not imposed a ban on spinal column and brain in the rendering process because to do so would be very expensive and basically unenforceable. As one rendering-plant employee told me, "Who would want the job of cutting out all those spinal columns and brains? You couldn't even get occasional workers to do it." But when asked why brain and spinal column are not banned from the human food supply in the United States, Hueston was circumspect, suggesting that I speak with someone at the Food Safety and Inspection Service.'

'Jacque Knight, a spokeswoman for the FSIS, was vague and seemed annoyed when asked whether brain or spinal cord was getting directly into sausage or other processed meats. "Since the Meat Act of 1906 we have never prohibited brain or spinal cord," she said. "It is part of the animal. However, it is not something people expect to find in meat. Therefore, as of May of last year, we have told our inspectors that if they suspect brain or spinal cord of getting into meat, they should report it." The inspectors' union expressed concern that it would be difficult for its members, already bogged down in other duties, to take on this additional task. The agency employs 7,535 inspectors in 6,200 meat and poultry slaughtering and processing plants. To date fifty-four reports have been filed and five plants have been found in violation of the rule. '

'The Rocky Mountain Laboratories is an unassuming NIH outpost hunkered in the shadow of the magnificent snow-crested Bitterroot Mountains. Built on a residential street in Hamilton, Montana, the red-brick structure stands out like a Brooks Brothers suit on Casual Friday. The lab was set up by the state in 1928 to study Rocky Mountain spotted fever, a deadly tick-borne disease that plagued the region. The people of Hamilton were so nervous about ticks going AWOL from the lab that a moat -- really, a puddle-deep trench -- was dug around its perimeter. Over time the laboratory has branched out to consider a wide range of infectious diseases, and has attracted, among other notables, a world-renowned team of experts on TSE. One of these is Byron Caughey, a strapping, bearded biochemist who looks nothing like the poet whose name he shares.'


http://www.mad-cow.org/mad_sheep.html#aaa



http://www.theatlantic.com/issues/98sep/madcow.htm



Dr. Will Hueston, a University of Minnesota veterinarian and expert on public health communications, was cited as saying that new and emerging diseases require public officials to offer straight talk, adding, "You need to be candid and straight-forward -- and you need to be first. In the face of an emerging (disease) issue ... if authoritative sources of information do not step forward, then people will fill that void by anything they can. You end up following rumors." Hueston was further quoted as saying public officials often show "a natural tendency to over-reassure, that everything's all right. ... The more you try to assure people that everything is all right, they think there's something really bad you're not telling."


http://archives.foodsafety.ksu.edu/animalnet/2005/12-2005/AnimalNet%20Dec.%2014_05.eml.html#story0




NOW, some facts Will Hueston, DVM, director of the University of Minnesota's Center for Animal Health and Food Safety fails to mention ;

J. Virol. doi:10.1128/JVI.02561-07 Copyright (c) 2008, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Evaluation of the Human Transmission Risk of an Atypical Bovine Spongiform Encephalopathy Prion Strain

***These results suggest that, in humans, BASE is a more virulent BSE strain and likely lymphotropic.


http://jvi.asm.org/cgi/content/abstract/JVI.02561-07v1?papetoc




USA MAD COW CASES IN ALABAMA AND TEXAS


***PLEASE NOTE***

USA BASE CASE, (ATYPICAL BSE), AND OR TSE (whatever they are calling it today), please note that both the ALABAMA COW, AND THE TEXAS COW, both were ''H-TYPE'', personal communication Detwiler et al Wednesday, August 22, 2007 11:52 PM. ...TSS




http://lists.iatp.org/listarchive/archive.cfm?listID=147&startrow=1081




2009 UPDATE ON ALABAMA AND TEXAS MAD COWS 2005 and 2006



http://bse-atypical.blogspot.com/2006/08/bse-atypical-texas-and-alabama-update.html



Monday, October 19, 2009


Atypical BSE, BSE, and other human and animal TSE in North America Update October 2009



http://bse-atypical.blogspot.com/2009/10/atypical-bse-bse-and-other-human-and.html



Wednesday, November 18, 2009


R-CALF: 40 Groups Disagree With USDA's Latest BSE Court Submission



http://bse-atypical.blogspot.com/2009/11/r-calf-40-groups-disagree-with-usdas.html





Monday, November 23, 2009

BSE GBR RISK ASSESSMENTS UPDATE NOVEMBER 23, 2009 COMMISSION OF THE EUROPEAN COMMUNITIES AND O.I.E.



http://docket-aphis-2006-0041.blogspot.com/2009/11/bse-gbr-risk-assessments-update.html






MARCH 2002

Livestock Mortalities:

Methods of Disposal and Their

Potential Costs

USDA/National Agricultural Statistics Service (NASS) estimates that in the year 2000,

approximately 4.1 million cattle died before they could be sent to slaughter (Table 2). Of these, 2.4 million were calves (under 500 lbs), with the balance of 1.7 million over 6 months of age (or, as reported, in excess of 500 lbs). ....END...TSS

NASS

Non-Ambulatory

Cattle and Calves

Released May 5, 2005, by the National Agricultural Statistics Service (NASS), Agricultural Statistics Board, U.S. Department

of Agriculture. For information on Non-ambulatory Cattle and Calves call Mike Miller at 720-3040, office hours 7:30 a.m. to

4:30 p.m. ET.

Cattle and Calves: Non-Ambulatory Number,

by Region and United States, 2003-2004

ALL NON-AMBULATORY CATTLE 2003 = 465,000

ALL NON-AMBULATORY CATTLE 2004 = 450,000

SNIP...END...TSS

Non-Ambulatory

Cattle and Calves

Released May 5, 2005, by the National Agricultural Statistics Service (NASS), Agricultural Statistics Board, U.S. Department

of Agriculture. For information on Non-ambulatory Cattle and Calves call Mike Miller at 720-3040, office hours 7:30 a.m. to

4:30 p.m. ET.

Non-Ambulatory Cattle and Calves

Non-ambulatory cattle and calves in the United States totaled 465,000 head during 2003 and

450,000 head during 2004. The number of non-ambulatory cattle 500 pounds or greater totaled

280,000 head in 2003 and 270,000 head in 2004. The number of calves under 500 pounds reported

as non-ambulatory totaled 185,000 head in 2003 and 180,000 head in 2004. ...SNIP...END

August 2004

04-021ANPR 04-021ANPR-68 N/A

An Economic and Environmental Assessment of Eliminating Specified Risk Materials and Cattle Mortalities from Existing Markets

snip...

USDA estimates 1.7 103 million cattle and 2.3656 million calves died prior to slaughter in 20022, for a. total species count of just under 4.1 million deaths. In 2001, USDA reported just over 4.2 million species deaths. The next step is to determine the number of nonambulatory cattle in the United States. No one knows the exact number; however, USDA estimates approximately 200,000 per year based on a survey conducted of American Association of Bovine Practitioners members3, bringing the estimated total number of dead and downer cattle and calves to about 4.3 - 4.4 million per year, roughly consistent with FDA’s estimate of 4.6 million.

USDA does, not regularly report cattle deaths by type, i.e. beef or diary, but it periodically conducts an industry survey to provide a detailed breakdown of the cattle and calf death losses by class, state and size group. From their most recent survey4 it is estimated that 69.4% of cattle deaths and 68,7% of calf deaths are from beef animals, with dairy animals accounting for the remaining 30.6% and 31.3% of cattle and calf deaths, respectively. Given the absence of updated data and little reason to expect these proportions have changed meaningfully over time, we apply these factors to the USDA total cattle and calf death loss estimates reported above to estimate current cattle and calf death loss in the beef and dairy industries (Table 1).


http://www.fda.gov/ohrms/DOCKETS/dailys/04/sep04/092104/04n-0264-c00142-vol22.pdf



Monday, October 19, 2009

Atypical BSE, BSE, and other human and animal TSE in North America Update
October 19, 2009


http://bse-atypical.blogspot.com/2009/10/atypical-bse-bse-and-other-human-and.html





Sunday, September 6, 2009

MAD COW USA 1997 SECRET VIDEO


http://madcowusda.blogspot.com/2009/09/mad-cow-usa-1997-video.html




U.S.A. HIDING MAD COW DISEASE VICTIMS AS SPORADIC CJD ? see video at bottom


http://creutzfeldt-jakob-disease.blogspot.com/2009/07/usa-hiding-mad-cow-disease-victims-as.html




DAMNING TESTIMONY FROM STANLEY PRUSINER THE NOBEL PEACE PRIZE WINNER ON PRIONS SPEAKING ABOUT ANN VENEMAN see video


http://maddeer.org/video/embedded/prusinerclip.html



2009 UPDATE ON ALABAMA AND TEXAS MAD COWS 2005 and 2006


http://bse-atypical.blogspot.com/2006/08/bse-atypical-texas-and-alabama-update.html





10,000,000+ LBS. of PROHIBITED BANNED MAD COW FEED I.E. MBM IN COMMERCE USA 2007

Date: March 21, 2007 at 2:27 pm PST RECALLS AND FIELD CORRECTIONS: VETERINARY MEDICINES -- CLASS II ___________________________________

PRODUCT

Bulk cattle feed made with recalled Darling’s 85% Blood Meal, Flash Dried, Recall # V-024-2007

CODE

Cattle feed delivered between 01/12/2007 and 01/26/2007

RECALLING FIRM/MANUFACTURER

Pfeiffer, Arno, Inc, Greenbush, WI. by conversation on February 5, 2007.

Firm initiated recall is ongoing.

REASON

Blood meal used to make cattle feed was recalled because it was cross-contaminated with prohibited bovine meat and bone meal that had been manufactured on common equipment and labeling did not bear cautionary BSE statement.

VOLUME OF PRODUCT IN COMMERCE

42,090 lbs.

DISTRIBUTION

WI

___________________________________

PRODUCT

Custom dairy premix products: MNM ALL PURPOSE Pellet, HILLSIDE/CDL Prot-Buffer Meal, LEE, M.-CLOSE UP PX Pellet, HIGH DESERT/ GHC LACT Meal, TATARKA, M CUST PROT Meal, SUNRIDGE/CDL PROTEIN Blend, LOURENZO, K PVM DAIRY Meal, DOUBLE B DAIRY/GHC LAC Mineral, WEST PIONT/GHC CLOSEUP Mineral, WEST POINT/GHC LACT Meal, JENKS, J/COMPASS PROTEIN Meal, COPPINI – 8# SPECIAL DAIRY Mix, GULICK, L-LACT Meal (Bulk), TRIPLE J – PROTEIN/LACTATION, ROCK CREEK/GHC MILK Mineral, BETTENCOURT/GHC S.SIDE MK-MN, BETTENCOURT #1/GHC MILK MINR, V&C DAIRY/GHC LACT Meal, VEENSTRA, F/GHC LACT Meal, SMUTNY, A-BYPASS ML W/SMARTA, Recall # V-025-2007

CODE

The firm does not utilize a code - only shipping documentation with commodity and weights identified.

RECALLING FIRM/MANUFACTURER

Rangen, Inc, Buhl, ID, by letters on February 13 and 14, 2007. Firm initiated recall is complete.

REASON

Products manufactured from bulk feed containing blood meal that was cross contaminated with prohibited meat and bone meal and the labeling did not bear cautionary BSE statement.

VOLUME OF PRODUCT IN COMMERCE

9,997,976 lbs.

DISTRIBUTION

ID and NV

END OF ENFORCEMENT REPORT FOR MARCH 21, 2007

http://www.fda.gov/bbs/topics/enforce/2007/ENF00996.html

NEW URL

http://www.fda.gov/Safety/Recalls/EnforcementReports/2007/ucm120446.htm


Subject: MAD COW FEED RECALL USA SEPT 6, 2006 1961.72 TONS IN COMMERCE AL, TN, AND WV

Date: September 6, 2006 at 7:58 am PST

PRODUCT

a) EVSRC Custom dairy feed, Recall # V-130-6; b) Performance Chick Starter, Recall # V-131-6; c) Performance Quail Grower, Recall # V-132-6; d) Performance Pheasant Finisher, Recall # V-133-6.

CODE None

RECALLING FIRM/MANUFACTURER

Donaldson & Hasenbein/dba J&R Feed Service, Inc., Cullman, AL, by telephone on June 23, 2006 and by letter dated July 19, 2006. Firm initiated recall is complete.

REASON

Dairy and poultry feeds were possibly contaminated with ruminant based protein.

VOLUME OF PRODUCT IN COMMERCE

477.72 tons

DISTRIBUTION

AL ______________________________

PRODUCT

a) Dairy feed, custom, Recall # V-134-6; b) Custom Dairy Feed with Monensin, Recall # V-135-6. CODE None. Bulk product

RECALLING FIRM/MANUFACTURER

Recalling Firm: Burkmann Feed, Greeneville, TN, by Telephone beginning on June 28, 2006.

Manufacturer: H. J. Baker & Bro., Inc., Albertville, AL. Firm initiated recall is complete.

REASON

Possible contamination of dairy feeds with ruminant derived meat and bone meal.

VOLUME OF PRODUCT IN COMMERCE

1,484 tons

DISTRIBUTION

TN and WV

http://www.fda.gov/bbs/topics/enforce/2006/ENF00968.html


Subject: MAD COW FEED RECALLS ENFORCEMENT REPORT FOR AUGUST 9, 2006 KY, LA, MS, AL, GA, AND TN 11,000+ TONS

Date: August 16, 2006 at 9:19 am PST

RECALLS AND FIELD CORRECTIONS: VETERINARY MEDICINE - CLASS II ______________________________

PRODUCT

Bulk custom made dairy feed, Recall # V-115-6

CODE None

RECALLING FIRM/MANUFACTURER

Hiseville Feed & Seed Co., Hiseville, KY, by telephone and letter on or about July 14, 2006. FDA initiated recall is ongoing.

REASON

Custom made feeds contain ingredient called Pro-Lak which may contain ruminant derived meat and bone meal.

VOLUME OF PRODUCT IN COMMERCE

Approximately 2,223 tons

DISTRIBUTION

KY

______________________________

PRODUCT

Bulk custom made dairy feed, Recall # V-116-6

CODE None

RECALLING FIRM/MANUFACTURER

Rips Farm Center, Tollesboro, KY, by telephone and letter on July 14, 2006. FDA initiated recall is ongoing.

REASON

Custom made feeds contain ingredient called Pro-Lak which may contain ruminant derived meat and bone meal.

VOLUME OF PRODUCT IN COMMERCE

1,220 tons

DISTRIBUTION

KY

______________________________

PRODUCT

Bulk custom made dairy feed, Recall # V-117-6

CODE None

RECALLING FIRM/MANUFACTURER

Kentwood Co-op, Kentwood, LA, by telephone on June 27, 2006. FDA initiated recall is completed.

REASON

Possible contamination of animal feed ingredients, including ingredients that are used in feed for dairy animals, with ruminant derived meat and bone meal.

VOLUME OF PRODUCT IN COMMERCE

40 tons

DISTRIBUTION

LA and MS

______________________________

PRODUCT

Bulk Dairy Feed, Recall V-118-6

CODE None

RECALLING FIRM/MANUFACTURER

Cal Maine Foods, Inc., Edwards, MS, by telephone on June 26, 2006. FDA initiated recall is complete.

REASON

Possible contamination of animal feed ingredients, including ingredients that are used in feed for dairy animals, with ruminant derived meat and bone meal.

VOLUME OF PRODUCT IN COMMERCE

7,150 tons

DISTRIBUTION

MS

______________________________

PRODUCT

Bulk custom dairy pre-mixes, Recall # V-119-6

CODE None

RECALLING FIRM/MANUFACTURER

Walthall County Co-op, Tylertown, MS, by telephone on June 26, 2006. Firm initiated recall is complete.

REASON

Possible contamination of dairy animal feeds with ruminant derived meat and bone meal.

VOLUME OF PRODUCT IN COMMERCE

87 tons

DISTRIBUTION

MS

______________________________

PRODUCT

Bulk custom dairy pre-mixes, Recall # V-120-6

CODE None

RECALLING FIRM/MANUFACTURER

Ware Milling Inc., Houston, MS, by telephone on June 23, 2006. Firm initiated recall is complete.

REASON

Possible contamination of dairy animal feeds with ruminant derived meat and bone meal.

VOLUME OF PRODUCT IN COMMERCE

350 tons

DISTRIBUTION

AL and MS

______________________________

PRODUCT

a) Tucker Milling, LLC Tm 32% Sinking Fish Grower, #2680-Pellet, 50 lb. bags, Recall # V-121-6; b) Tucker Milling, LLC #31120, Game Bird Breeder Pellet, 50 lb. bags, Recall # V-122-6; c) Tucker Milling, LLC #31232 Game Bird Grower, 50 lb. bags, Recall # V-123-6; d) Tucker Milling, LLC 31227-Crumble, Game Bird Starter, BMD Medicated, 50 lb bags, Recall # V-124-6; e) Tucker Milling, LLC #31120, Game Bird Breeder, 50 lb bags, Recall # V-125-6; f) Tucker Milling, LLC #30230, 30 % Turkey Starter, 50 lb bags, Recall # V-126-6; g) Tucker Milling, LLC #30116, TM Broiler Finisher, 50 lb bags, Recall # V-127-6

CODE

All products manufactured from 02/01/2005 until 06/20/2006

RECALLING FIRM/MANUFACTURER

Recalling Firm: Tucker Milling LLC, Guntersville, AL, by telephone and visit on June 20, 2006, and by letter on June 23, 2006. Manufacturer: H. J. Baker and Brothers Inc., Stamford, CT. Firm initiated recall is ongoing.

REASON

Poultry and fish feeds which were possibly contaminated with ruminant based protein were not labeled as "Do not feed to ruminants".

VOLUME OF PRODUCT IN COMMERCE

7,541-50 lb bags

DISTRIBUTION

AL, GA, MS, and TN

END OF ENFORCEMENT REPORT FOR AUGUST 9, 2006

###

http://www.fda.gov/bbs/topics/ENFORCE/2006/ENF00964.html


Subject: MAD COW FEED RECALL MI MAMMALIAN PROTEIN VOLUME OF PRODUCT IN COMMERCE 27,694,240 lbs

Date: August 6, 2006 at 6:14 pm PST

PRODUCT

Bulk custom dairy feds manufactured from concentrates, Recall # V-113-6

CODE

All dairy feeds produced between 2/1/05 and 6/16/06 and containing H. J. Baker recalled feed products.

RECALLING FIRM/MANUFACTURER

Vita Plus Corp., Gagetown, MI, by visit beginning on June 21, 2006. Firm initiated recall is complete.

REASON

The feed was manufactured from materials that may have been contaminated with mammalian protein.

VOLUME OF PRODUCT IN COMMERCE

27,694,240 lbs

DISTRIBUTION

MI

END OF ENFORCEMENT REPORT FOR AUGUST 2, 2006

###

http://www.fda.gov/bbs/topics/enforce/2006/ENF00963.html



THIS LIST IS ENDLESS, SEE FULL TEXT MAD COW PROTEIN SRMs IN COMMERCE. remember this, .005 gram of mad cow tainted material is lethal enough to kill one cow. ...tss


http://madcowspontaneousnot.blogspot.com/2008/02/specified-risk-materials-srm.html



http://madcowspontaneousnot.blogspot.com/2008/01/january-2008-update-on-feed-enforcement.html



Geographical BSE Risk (GBR) assessments covering 2000-2006

Date : 01.08.2006


http://www.efsa.europa.eu/EFSA/Scientific_Document/GBR_assessments_table_Overview_assessed_countries_2002-2006.pdf



Audit Report

Animal and Plant Health Inspection Service

Bovine Spongiform Encephalopathy (BSE) Surveillance Program - Phase II

and

Food Safety and Inspection Service

Controls Over BSE Sampling, Specified Risk Materials, and Advanced Meat Recovery Products - Phase III

Report No. 50601-10-KC January 2006

Finding 2 Inherent Challenges in Identifying and Testing High-Risk Cattle Still Remain

Our prior report identified a number of inherent problems in identifying and testing high-risk cattle. We reported that the challenges in identifying the universe of high-risk cattle, as well as the need to design procedures to obtain an appropriate representation of samples, was critical to the success of the BSE surveillance program. The surveillance program was designed to target nonambulatory cattle, cattle showing signs of CNS disease (including cattle testing negative for rabies), cattle showing signs not inconsistent with BSE, and dead cattle. Although APHIS designed procedures to ensure FSIS condemned cattle were sampled and made a concerted effort for outreach to obtain targeted samples, industry practices not considered in the design of the surveillance program reduced assurance that targeted animals were tested for BSE.

USDA/OIG-A/50601-10-KC Page 27

observe these animals ante mortem when possible to assure the animals from the target population are ultimately sampled and the clinical signs evaluated.

snip...


http://www.usda.gov/oig/webdocs/50601-10-KC.pdf



GAO-05-51 October 2004 FOOD SAFETY

over 500 customers receiving potentially BSE contaminated beef .....

* GAO-05-51 October 2004 FOOD SAFETY (over 500 customers receiving potentially BSE contaminated beef) - TSS 10/20/04

October 2004 FOOD SAFETY USDA and FDA Need to Better Ensure Prompt and Complete Recalls of Potentially Unsafe Food

snip...

REPORTS

1. Food Safety: USDA and FDA Need to Better Ensure Prompt and Complete Recalls of Potentially Unsafe Food. GAO-05-51, October 7.tss


http://www.gao.gov/new.items/d0551.pdf



Highlights -


http://www.gao.gov/highlights/d0551high.pdf



3. Mad Cow Disease: FDA's Management of the Feed Ban Has Improved, but Oversight Weaknesses Continue to Limit Program Effectiveness. GAO-05-101, Feb. 25.


www.gao.gov/cgi-bin/getrpt?GAO-05-101



Highlights -


www.gao.gov/highlights/d05101high.pdf



SADLY, DEC 2005 SHOWS THAT WE STILL HAVE A SERIOUS PROBLEM WITH BSE/TSE MAD COW DISEASE FEED

GAO

GAO-06-157R FDA Feed Testing Program

October 11, 2005

SNIP...FULL TEXT 29 PAGES ;


http://www.gao.gov/new.items/d06157r.pdf



Mad Cow Disease: An Evaluation of a Small Feed Testing Program FDA Implemented in 2003 With Recommendations for Making the Program a Better Oversight Tool. GAO-06-157R, October 11


http://www.gao.gov/cgi-bin/getrpt?GAO-06-157R



PrPSc distribution of a natural case of bovine spongiform encephalopathy

Yoshifumi Iwamaru, Yuka Okubo, Tamako Ikeda, Hiroko Hayashi, Mori- kazu Imamura, Takashi Yokoyama and Morikazu Shinagawa Priori Disease Research Center, National Institute of Animal Health, 3-1-5 Kannondai, Tsukuba 305-0856 Japan gan@affrc.go.jp

Abstract

Bovine spongiform encephalopathy (BSE) is a disease of cattle that causes progressive neurodegeneration of the central nervous system. Infectivity of BSE agent is accompanied with an abnormal isoform of prion protein (PrPSc). The specified risk materials (SRM) are tissues potentially carrying BSE infectivity. The following tissues are designated as SRM in Japan: the skull including the brain and eyes but excluding the glossa and the masse- ter muscle, the vertebral column excluding the vertebrae of the tail, spinal cord, distal illeum. For a risk management step, the use of SRM in both animal feed or human food has been prohibited. However, detailed PrPSc distribution remains obscure in BSE cattle and it has caused controversies about definitions of SRM. Therefore we have examined PrPSc distribution in a BSE cattle by Western blotting to reassess definitions of SRM. The 11th BSE case in Japan was detected in fallen stock surveillance. The carcass was stocked in the refrigerator. For the detection of PrPSc, 200 mg of tissue samples were homogenized. Following collagenase treatment, samples were digested with proteinase K. After digestion, PrPSc was precipitated by sodium phosphotungstate (PTA). The pellets were subjected to Western blotting using the standard procedure. Anti-prion protein monoclonal antibody (mAb) T2 conjugated horseradish peroxidase was used for the detection of PrPSc. PrPSc was detected in brain, spinal cord, dorsal root ganglia, trigeminal ganglia, sublingual ganglion, retina. In addition, PrPSc was also detected in the peripheral nerves (sciatic nerve, tibial nerve, vagus nerve). Our results suggest that the currently accepted definitions of SRM in 9/13/2005

179 Page 10 of 17

BSE cattle may need to be reexamined.

T. Kitamoto (Ed.) PRIONS Food and Drug Safety

================

ALSO from the International Symposium of Prion Diseases held in Sendai, October 31, to November 2, 2004; Bovine spongiform encephalopathy (BSE) in Japan

snip...


http://www.fsis.usda.gov/OPPDE/Comments/03-025IFA/03-025IFA-2.pdf



Detection and Localization of PrPSc in the Skeletal Muscle Thu Mar 2, 2006 10:40 70.110.86.250

© 2006 American Society for Investigative Pathology

Detection and Localization of PrPSc in the Skeletal Muscle of Patients with Variant, Iatrogenic, and Sporadic Forms of Creutzfeldt-Jakob Disease Alexander H. Peden, Diane L. Ritchie, Mark W. Head and James W. Ironside From the National Creutzfeldt-Jakob Disease Surveillance Unit and Division of Pathology, School of Molecular and Clinical Medicine, University of Edinburgh, Western General Hospital, Edinburgh, United Kingdom

Variant Creutzfeldt-Jakob disease (vCJD) differs from other human prion diseases in that the pathogenic prion protein PrPSc can be detected to a greater extent at extraneuronal sites throughout the body, principally within lymphoid tissues. However, a recent study using a high-sensitivity Western blotting technique revealed low levels of PrPSc in skeletal muscle from a quarter of Swiss patients with sporadic CJD (sCJD). This posed the question of whether PrPSc in muscle could also be detected in vCJD, sCJD, and iatrogenic (iCJD) patients from other populations. Therefore, we have used the same high-sensitivity Western blotting technique, in combination with paraffin-embedded tissue blotting, to screen for PrPSc in muscle tissue specimens taken at autopsy from 49 CJD patients in the United Kingdom. These techniques identified muscle PrPSc in 8 of 17 vCJD, 7 of 26 sCJD, and 2 of 5 iCJD patients. Paraffin-embedded tissue blotting analysis showed PrPSc in skeletal muscle in localized anatomical structures that had the morphological and immunohistochemical characteristics of nerve fibers. The detection of PrPSc in muscle tissue from all forms of CJD indicates the possible presence of infectivity in these tissues, suggesting important implications for assessing the potential risk of iatrogenic spread via contaminated surgical instruments.


http://ajp.amjpathol.org/cgi/content/abstract/168/3/927



Prions in Skeletal Muscles of Deer with Chronic Wasting Disease

Rachel C. Angers,1* Shawn R. Browning,1*† Tanya S. Seward,2 Christina J. Sigurdson,4‡ Michael W. Miller,5 Edward A. Hoover,4 Glenn C. Telling1,2,3§ 1Department of Microbiology, Immunology and Molecular Genetics, 2Sanders Brown Center on Aging, 3Department of Neurology, University of Kentucky, Lexington, KY 40536, USA. 4Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, CO 80523, USA. 5Colorado Division of Wildlife, Wildlife Research Center, Fort Collins, CO 80526, USA. *These authors contributed equally to this work. †Present address: Department of Infectology, Scripps Research Institute, 5353 Parkside Drive, RF-2, Jupiter, Florida, 33458, USA. ‡Present address: Institute of Neuropathology, University of Zurich, Schmelzbergstrasse 12, 8091 Zurich, Switzerland. §To whom correspondence should be addressed: E-mail: gtell2@uky.edu

Prions are transmissible proteinaceous agents of mammals that cause fatal neurodegenerative diseases of the central nervous system (CNS). The presence of infectivity in skeletal muscle of experimentally infected mice raised the possibility that dietary exposure to prions might occur through meat consumption (1). Chronic wasting disease (CWD), an enigmatic and contagious prion disease of North American cervids, is of particular concern. The emergence of CWD in an increasingly wide geographic area and the interspecies transmission of bovine spongiform encephalopathy (BSE) to humans as variant Creutzfeldt Jakob disease (vCJD) have raised concerns about zoonotic transmission of CWD. To test whether skeletal muscle of diseased cervids.........SNIP....END...TSS

Monday, February 4, 2008

USDA CERTIFIED H-BASE MAD COW SCHOOL LUNCH PROGRAM

PLEASE NOTE, this disgusting video is just another example of just how terribly flawed the BSE surveillance and testing program has been over the past decades.

THIS video also proves what the GAO and OIG have been stating for years, that HIGH RISK SUSPECT MAD COW animals have been entering the food chain in the USA for years, and fed to humans and animals for human consumption. LET know one tell you any different, this plant is but one of many, they just got caught $$$

did you check out the waterboarding, without the board, of the high risk suspect mad cow with the high pressure water hose $

what has happened to humanity $

what have we become as humans $


http://cjdmadcowbaseoct2007.blogspot.com/2008/02/usda-certified-h-base-mad-cow-school.html



Sunday, February 17, 2008

Release No. 0046.08 Statement by Secretary of Agriculture Ed Schafer Regarding Hallmark/Westland Meat Packing Company Two Year Product Recall Release No. 0046.08 Contact: USDA Press Office (202) 720-4623


http://cjdmadcowbaseoct2007.blogspot.com/2008/02/release-no-004608-statement-by.html



SCHOOL LUNCH PROGRAM FROM DOWNER CATTLE UPDATE


http://downercattle.blogspot.com/



Blog Archive

2008 (8)

March (6)

California DOWNER COW meat worker: I was following...


http://downercattle.blogspot.com/2008/03/california-downer-cow-meat-worker-i-was.html



USDA QUESTIONS AND ANSWERS HALLMARK/WESTLAND MEAT


http://downercattle.blogspot.com/2008/03/usda-questions-and-answers.html



USDA to Hallmark: We want our plaque back


http://downercattle.blogspot.com/2008/03/usda-to-hallmark-we-want-our-plaque.html



House committee subpoenas Hallmark/Westland CEO


http://downercattle.blogspot.com/2008/03/house-committee-subpoenas.html



California lists possible recipients of recalled


http://downercattle.blogspot.com/2008/03/california-lists-possible-recipients-of.html



To the hard working employees of USDA and


http://downercattle.blogspot.com/2008/03/to-hard-working-employees-of-usda-and.html



February (2)

BEEF RECALL NATIONWIDE - SCHOOL LUNCH PROGRAM UPDATE


http://downercattle.blogspot.com/2008_02_01_archive.html



TRANSCRIPT: Technical Briefing - Hallmark/Westland Meat Packing Company


http://downercattle.blogspot.com/





TSS

Saturday, March 8, 2008

California DOWNER COW meat worker: I was following orders

Saturday, March 8, 2008 California DOWNER COW meat worker: I was following orders Calif. meat worker: I was following orders

ADELANTO, Calif. (AP) — A former slaughterhouse worker who was videotaped abusing ailing cattle in a case that led to the largest beef recall in U.S. history said in a jailhouse interview that he was only following orders.

Luis Sanchez said he felt bad when he saw how the cows were treated at Chino-based Westland/Hallmark Meat Co., and insisted his boss taught him to use a forklift to move so-called downer cows along the slaughter line.

HISTORIC RECALL: Meat plant concerns raised for years

LEGAL LOOPHOLE: Government sued over ailing cattle

"That's how I was taught. He taught me to do the work. I didn't know it was a serious crime," Sanchez told the San Bernardino Sun in an interview published Friday.

Sanchez, an illegal immigrant from Mexico, was being held at the Adelanto Detention Center on immigration charges. He was charged with animal cruelty in the slaughterhouse case, but he also faced charges in two unrelated drug cases.

Sanchez's ex-boss, Daniel Ugarte Navarro, 49, has pleaded not guilty to five felony counts of animal abuse and three misdemeanor counts of illegal movement of a non-ambulatory animal. The counts carry a maximum prison sentence of 5 years, 8 months, prosecutors have said.

Navarro will be assigned an attorney by the county public defender's office at his March 24 arraignment.

Last month, the Agriculture Department issued the recall after the Humane Society of the United States released undercover video of workers forcing sick and crippled cows to stand with electric prods and forklifts.

Sanchez appeared in the video using an electric prod.

Sanchez said he learned the company was handling the cows differently than other slaughterhouses from truck drivers who brought the animals to the plant. He said his supervisor told the workers to use care when federal inspectors were around.

Sanchez, who first came to the slaughterhouse about 10 years ago, said he doesn't understand why he's in jail.

"I think it's unjust that I'm here. Where are the people in charge?" he told the newspaper.

Copyright 2008 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


http://www.usatoday.com/money/industries/food/2008-03-08-slaughterhouse-abuse_N.htm



Calif. meat worker: I was following orders

no doubt! i believe the guy, and i believe this practice of allowing downers into the food supply is wide spread.

here is just one more example $$$

Originally posted by worried about the industry

If the sick cattle don't get into the cooler how can anybody make a profit?

It is people like you that will cause the beef industry to colapse with your attitude. Get real. And if you believe as you say I hope you get the first bite of that sick animal.

-------------------------------------------------------------------------------- 3/6/2008 1:46 PM Posted By: GW =====================================================snip...end...TSS

YOU REALLY DON'T THINK that all these downers are just buried $$$

Animal Mortality Figures

The U.S. Department of Agriculture (USDA) estimates 1.7103 million cattle and 2.3656 million calves died prior to slaughter in 2002, for a total of just under 4.1 million deaths.

snip...

Cattle, however, with their heavier body weights, comprise approximately 67 percent of the total weight of all mammalian livestock mortalities. In 2002, the total weight for cattle was 2.7 billion pounds. Beef cattle account for the largest proportion of farm, ranch, and feedlot mortality, in respect to weight.

snip...

Focus on Non-Ambulatory Cattle

Non-ambulatory cattle have been estimated by USDA to be approximately 200,000 head per year based on a 1999 American Association of Bovine Practitioners survey.(2) It is proposed that this estimate understates the condition by not fully accounting for feedlot cattle of younger ages commonly affected with metabolic and or respiratory disorders that often present neurological-like clinical symptoms and thus described as non-ambulatory. It is impossible to give accurate figures on incidence because of variations in nomenclature and the accuracy of diagnosis. Because it is a syndrome until an accurate diagnosis is confirmed, the exact incidence is speculative.


http://www.rendermagazine.com/October2004/TechTopics.html


MARCH 2002

Livestock Mortalities:

Methods of Disposal and Their

Potential Costs

USDA/National Agricultural Statistics Service (NASS) estimates that in the year 2000,

approximately 4.1 million cattle died before they could be sent to slaughter (Table 2). Of these, 2.4 million were calves (under 500 lbs), with the balance of 1.7 million over 6 months of age (or, as reported, in excess of 500 lbs). ....END...TSS

NASS

Non-Ambulatory

Cattle and Calves

Released May 5, 2005, by the National Agricultural Statistics Service (NASS), Agricultural Statistics Board, U.S. Department

of Agriculture. For information on Non-ambulatory Cattle and Calves call Mike Miller at 720-3040, office hours 7:30 a.m. to

4:30 p.m. ET.

Cattle and Calves: Non-Ambulatory Number,

by Region and United States, 2003-2004

ALL CATTLE 2003 = 465,000

ALL CATTLE 2004 = 450,000

SNIP...END...TSS

Non-Ambulatory

Cattle and Calves

Released May 5, 2005, by the National Agricultural Statistics Service (NASS), Agricultural Statistics Board, U.S. Department

of Agriculture. For information on Non-ambulatory Cattle and Calves call Mike Miller at 720-3040, office hours 7:30 a.m. to

4:30 p.m. ET.

Non-Ambulatory Cattle and Calves

Non-ambulatory cattle and calves in the United States totaled 465,000 head during 2003 and

450,000 head during 2004. The number of non-ambulatory cattle 500 pounds or greater totaled

280,000 head in 2003 and 270,000 head in 2004. The number of calves under 500 pounds reported

as non-ambulatory totaled 185,000 head in 2003 and 180,000 head in 2004.

...SNIP...END...TSS

Friday, March 7, 2008

USDA QUESTIONS AND ANSWERS HALLMARK/WESTLAND MEAT PACKING CO. March 6, 2008

QUESTIONS AND ANSWERS HALLMARK/WESTLAND MEAT PACKING CO.

March 6, 2008

Consumer Concerns

Q. My child/school recently consumed Hallmark/Westland products. What is the risk to children's health?

SEE FULL TEXT ;


http://downercattle.blogspot.com/2008/03/usda-questions-and-answers.html


Wednesday, February 27, 2008

BEEF RECALL NATIONWIDE - SCHOOL LUNCH PROGRAM UPDATE


http://downercattle.blogspot.com/2008/02/beef-recall-nationwide-school-lunch.html


Thursday, March 6, 2008

California lists possible recipients of recalled non-ambulatory 'DOWNER' (high potential for TSE) Hallmark beef


http://downercattle.blogspot.com/2008/03/california-lists-possible-recipients-of.html


Thursday, March 6, 2008

House committee subpoenas Hallmark/Westland CEO - i call for an investigation of the investigators


http://downercattle.blogspot.com/2008/03/house-committee-subpoenas.html


Thursday, March 6, 2008

USDA to Hallmark: We want our plaque back Legal/Regulatory News


http://downercattle.blogspot.com/2008/03/usda-to-hallmark-we-want-our-plaque.html


Thursday, March 6, 2008

To the hard working employees of USDA and their untiring efforts to protect our childrens food supply


http://downercattle.blogspot.com/2008/03/to-hard-working-employees-of-usda-and.html


In this context, a word is in order about the US testing program. After the discovery of the first (imported) cow in 2003, the magnitude of testing was much increased, reaching a level of >400,000 tests in 2005 (Figure 4). Neither of the 2 more recently indigenously infected older animals with nonspecific clinical features would have been detected without such testing, and neither would have been identified as atypical without confirmatory Western blots. Despite these facts, surveillance has now been decimated to 40,000 annual tests (USDA news release no. 0255.06, July 20, 2006) and invites the accusation that the United States will never know the true status of its involvement with BSE.


http://www.cdc.gov/ncidod/EID/vol12no12/06-0965.htm


PAUL BROWN COMMENT TO ME ON THIS ISSUE

Tuesday, September 12, 2006 11:10 AM

"Actually, Terry, I have been critical of the USDA handling of the mad cow issue for some years, and with Linda Detwiler and others sent lengthy detailed critiques and recommendations to both the USDA and the Canadian Food Agency."



http://lists.iatp.org/listarchive/archive.cfm?listID=147&startrow=1081



3/6/2008

i call for an investigation of the investigators

House committee subpoenas Hallmark/Westland CEO The subpoena orders him to testify at a March 12 hearing titled "Regulatory Failure: Must America Live With Unsafe Food?"<<< what a hoot. the ones that should be subpoenad and held accountable are the very ones on the committee. they have failed the public for years about BSE risk and regulations. the very people that are going to investigate this thing are the very folks responsible for all the children and elderly that were exposed to the potential of mad cow via non-ambulatory i.e. DOWNERS, the most likely to have a TSE. waxman et al have been claiming to be concerned about BSE aka mad cow disease's and one issue was the non-ambulatory 'downer' cattle, and i quote waxman; Failure To Test Staggering Cow May Reflect Wider Problems Rep. Waxman raises concerns that the recent failure of USDA to test an impaired cow for BSE may not be an isolated incident, citing the failure of USDA to monitor whether cows condemned for central nervous system symptoms are actually tested for mad cow disease.



http://reform.democrats.house.gov/documents/20040607142914-86912.pdf



http://oversight.house.gov/documents/20040607142914-86912.pdf




folks, that was in 2004. why, in 2008, why are we still discussing the same failures $$$

THE PEOPLE BELOW SHOULD ALL BE SUBPOENAED AS WELL FOR THEIR CONTINUED FAILURES TO PROTECT THE CONSUMER FROM MAD COW DISEASE. and i call for an investigation of the investigators below. why in 2008 are we still floundering $$$

Committee on Energy and Commerce Subcommittee on Oversight and Investigations




http://energycommerce.house.gov/Subcommittees/ovin.shtml




CJD QUESTIONNAIRE


http://cjdquestionnaire.blogspot.com/



Specified Risk Material SRM see tons and tons of BANNED mad cow feed SRMs IN COMMERCE USA, the other safe guard USDA et al keeps boasting about, that has failed terribly along with the BSE surveillance and BSE testing protocols. see for yourself ;



http://madcowspontaneousnot.blogspot.com/2008/02/specified-risk-materials-srm.html



Terry S. Singeltary Sr. P.O. Box 42 Bacliff, Texas USA 77518

Friday, March 7, 2008

USDA QUESTIONS AND ANSWERS HALLMARK/WESTLAND MEAT PACKING CO. March 6, 2008

QUESTIONS AND ANSWERS HALLMARK/WESTLAND MEAT PACKING CO.

March 6, 2008

Consumer Concerns

Q. My child/school recently consumed Hallmark/Westland products. What is the risk to children's health?

A. Extremely remote. USDA's Agricultural Marketing Service (AMS) has every production lot of ground beef tested by independent laboratories for certain pathogens and indicator organisms. Those lots that have positive findings of E. coli 0157:H7 or Salmonella are prohibited from Federal food and nutrition programs and USDA's Food Safety and Inspection Service is notified. AMS had only one positive test result at Hallmark/Westland and this product was removed from the AMS supply chain and not delivered to any Federal food and nutrition program.

USDA is confident in the safety of the food supply. Human and animal health is protected by a system of interlocking safeguards, which also include the removal of specified risk materials—those tissues that studies have demonstrated could contain the bovine spongiform encephalopathy (BSE) agent in infected cattle—from the human food chain, along with the U.S. Food and Drug Administration's 1997 ruminant to ruminant feed ban.

The cattle at the Hallmark/Westland Meat Packing Company passed ante-mortem inspection before slaughter. While the federal government has multiple regulations regarding BSE in place, the prevalence of the disease in the United States is extremely low. Since June 1, 2004, APHIS has sampled more than 759,000 animals and, to date, only 2 animals have tested positive for BSE under the program.

Q. How can I find out whether my school or school district served any Hallmark/Westland products to my children?

A. State Distributing Agencies that handle commodities purchased by USDA have records on where Hallmark/Westland products were delivered within the State. Contact information is available at www.usda.gov/actions.


http://www.usda.gov/wps/portal/usdahome?contentidonly=true&contentid=Consumer_Concerns.xml


Release No. 0048.08 Contact: Office of Communications (202)720-4623

QUESTIONS AND ANSWERS HALLMARK/WESTLAND MEAT PACKING CO.

Updated: March 07, 2008

USDA Actions

Recall Information

Bovine Spongiform Encephalopathy Control Measures

Consumer Concerns

Humane Handling

International Trade


http://www.usda.gov/wps/portal/usdahome?contentidonly=true&contentid=2008/02/0048.xml


USDA ET AL PROTECTING THEIR OWN $$$

Congress Wants More Info on Beef Recall By ERICA WERNER – 1 day ago

WASHINGTON (AP) — Lawmakers demanded Thursday that the Agriculture Department disclose which retailers sold meat that was recently recalled in the nation's largest beef recall.

Richard Raymond, the department's undersecretary for food safety, told angry Democrats on the House Appropriations agriculture subcommittee that the information is proprietary and can't be made public.

Some 10,000 consignees — from producers to retail establishments — received the potentially tainted meat from the Westland/Hallmark Meat Co. in Chino, Calif., Raymond said. But he said he couldn't reveal which ones, and most of the meat had already been eaten because the recall stretched back two years.

Westland/Hallmark recalled 143 million pounds of beef last month after the Humane Society of the United States released undercover video of cattle being abused and cows that couldn't walk being prodded to slaughter.

Democratic lawmakers said it was unacceptable for the public not to know where the meat went. So-called "downer" cattle pose a higher risk of E. coli, salmonella and other illnesses.

"This is not proprietary information. This is information that is directly engaged in the health and safety of the American people, which we have a responsibility, along with you, to protect," said Rep. Maurice Hinchey, D-N.Y.

Hinchey demanded a list of the retailers by next week. Raymond said he'd consult with Agriculture Department attorneys on whether he could comply.

The Bush administration has opposed publicizing retailers' names in meat recalls, but the Agriculture Department's Food Safety and Inspection Service proposed a rule change two years ago that would allow such disclosure.

The rule still hasn't been finalized. Raymond said it was in final review at the Agriculture Department before being sent to the White House budget office.

"It is in the final stages of clearance," he said.

Democrats contended the Bush administration was delaying the rule under pressure from industry.

California, unique among states, has its own law allowing for disclosure of the names of the retailers where recalled beef was available. The law took effect just last July. A 120-page list of retailers is posted on the California Department of Public Health Web site at http://dhs.ca.gov/ and is still being updated, California officials said.

The rules on public disclosure are different for meat that went into federal programs, which more than 50 million pounds of the Westland/Hallmark meat did, mostly school lunches. Individual state distributing agencies have their own approaches for disclosing information about the recalled meat.

Contacts for state distributing agencies are at

http://www.fns.usda.gov/fdd/contacts/sdacontacts.htm.


To date, of the 50.3 million pounds of Westland/Hallmark product in the federal food and nutrition programs, 31 million pounds have been consumed, 13.9 million pounds are on hold, and 6.5 million pounds are being traced, according to USDA.


http://ap.google.com/article/ALeqM5gjgIDJ5Z2xZSLp6TUi-kRcCFXmPgD8V855IG0


Animal Mortality Figures

The U.S. Department of Agriculture (USDA) estimates 1.7103 million cattle and 2.3656 million calves died prior to slaughter in 2002, for a total of just under 4.1 million deaths.

snip...

Cattle, however, with their heavier body weights, comprise approximately 67 percent of the total weight of all mammalian livestock mortalities. In 2002, the total weight for cattle was 2.7 billion pounds. Beef cattle account for the largest proportion of farm, ranch, and feedlot mortality, in respect to weight.

snip...

Focus on Non-Ambulatory Cattle

Non-ambulatory cattle have been estimated by USDA to be approximately 200,000 head per year based on a 1999 American Association of Bovine Practitioners survey.(2) It is proposed that this estimate understates the condition by not fully accounting for feedlot cattle of younger ages commonly affected with metabolic and or respiratory disorders that often present neurological-like clinical symptoms and thus described as non-ambulatory. It is impossible to give accurate figures on incidence because of variations in nomenclature and the accuracy of diagnosis. Because it is a syndrome until an accurate diagnosis is confirmed, the exact incidence is speculative.


http://www.rendermagazine.com/October2004/TechTopics.html


MARCH 2002

Livestock Mortalities:

Methods of Disposal and Their

Potential Costs

USDA/National Agricultural Statistics Service (NASS) estimates that in the year 2000,

approximately 4.1 million cattle died before they could be sent to slaughter (Table 2). Of these, 2.4 million were calves (under 500 lbs), with the balance of 1.7 million over 6 months of age (or, as reported, in excess of 500 lbs). ....END...TSS

NASS

Non-Ambulatory

Cattle and Calves

Released May 5, 2005, by the National Agricultural Statistics Service (NASS), Agricultural Statistics Board, U.S. Department

of Agriculture. For information on Non-ambulatory Cattle and Calves call Mike Miller at 720-3040, office hours 7:30 a.m. to

4:30 p.m. ET.

Cattle and Calves: Non-Ambulatory Number,

by Region and United States, 2003-2004

ALL NON-AMBULATORY CATTLE 2003 = 465,000

ALL NON-AMBULATORY CATTLE 2004 = 450,000

SNIP...END...TSS

Non-Ambulatory

Cattle and Calves

Released May 5, 2005, by the National Agricultural Statistics Service (NASS), Agricultural Statistics Board, U.S. Department

of Agriculture. For information on Non-ambulatory Cattle and Calves call Mike Miller at 720-3040, office hours 7:30 a.m. to

4:30 p.m. ET.

Non-Ambulatory Cattle and Calves

Non-ambulatory cattle and calves in the United States totaled 465,000 head during 2003 and

450,000 head during 2004. The number of non-ambulatory cattle 500 pounds or greater totaled

280,000 head in 2003 and 270,000 head in 2004. The number of calves under 500 pounds reported

as non-ambulatory totaled 185,000 head in 2003 and 180,000 head in 2004. ...SNIP...END

=======================================================

USDA states ;

>>>Human and animal health is protected by a system of interlocking safeguards, which also include the removal of specified risk materials—those tissues that studies have demonstrated could contain the bovine spongiform encephalopathy (BSE) agent in infected cattle—from the human food chain, along with the U.S. Food and Drug Administration's 1997 ruminant to ruminant feed ban. <<<


href="http://www.fda.gov/Safety/Recalls/EnforcementReports/2007/ucm120446.htm">http://www.fda.gov/Safety/Recalls/EnforcementReports/2007/ucm120446.htm



Subject: MAD COW FEED RECALL USA SEPT 6, 2006 1961.72 TONS IN COMMERCE AL, TN, AND WV Date: September 6, 2006 at 7:58 am PST PRODUCT a) EVSRC Custom dairy feed, Recall # V-130-6; b)

snip...

PLEASE SEE SOME OF THE REST OF THE MAD COW FEED BAN SRM VIOLATIONS ;

http://madcowspontaneousnot.blogspot.com/2008/02/specified-risk-materials-srm.html


>>>USDA STATES ; While the federal government has multiple regulations regarding BSE in place, the prevalence of the disease in the United States is extremely low. Since June 1, 2004, APHIS has sampled more than 759,000 animals and, to date, only 2 animals have tested positive for BSE under the program. <<<>400,000 tests in 2005 (Figure 4). Neither of the 2 more recently indigenously infected older animals with nonspecific clinical features would have been detected without such testing, and neither would have been identified as atypical without confirmatory Western blots. Despite these facts, surveillance has now been decimated to 40,000 annual tests (USDA news release no. 0255.06, July 20, 2006) and invites the accusation that the United States will never know the true status of its involvement with BSE.


http://www.cdc.gov/ncidod/EID/vol12no12/06-0965.htm


PAUL BROWN COMMENT TO ME ON THIS ISSUE

Tuesday, September 12, 2006 11:10 AM

"Actually, Terry, I have been critical of the USDA handling of the mad cow issue for some years, and with Linda Detwiler and others sent lengthy detailed critiques and recommendations to both the USDA and the Canadian Food Agency."


http://lists.iatp.org/listarchive/archive.cfm?listID=147&startrow=1081




CDC DR. PAUL BROWN TSE EXPERT COMMENTS 2006

The U.S. Department of Agriculture was quick to assure the public earlier this week that the third case of mad cow disease did not pose a risk to them, but what federal officials have not acknowledged is that this latest case indicates the deadly disease has been circulating in U.S. herds for at least a decade.

The second case, which was detected last year in a Texas cow and which USDA officials were reluctant to verify, was approximately 12 years old.

These two cases (the latest was detected in an Alabama cow) present a picture of the disease having been here for 10 years or so, since it is thought that cows usually contract the disease from contaminated feed they consume as calves. The concern is that humans can contract a fatal, incurable, brain-wasting illness from consuming beef products contaminated with the mad cow pathogen.

"The fact the Texas cow showed up fairly clearly implied the existence of other undetected cases," Dr. Paul Brown, former medical director of the National Institutes of Health's Laboratory for Central Nervous System Studies and an expert on mad cow-like diseases, told United Press International. "The question was, 'How many?' and we still can't answer that."

Brown, who is preparing a scientific paper based on the latest two mad cow cases to estimate the maximum number of infected cows that occurred in the United States, said he has "absolutely no confidence in USDA tests before one year ago" because of the agency's reluctance to retest the Texas cow that initially tested positive.

USDA officials finally retested the cow and confirmed it was infected seven months later, but only at the insistence of the agency's inspector general.

"Everything they did on the Texas cow makes everything USDA did before 2005 suspect," Brown said. ...snip...end


http://www.upi.com/ConsumerHealthDaily/view.php?StoryID=20060315-055557-1284r


CDC - Bovine Spongiform Encephalopathy and Variant Creutzfeldt ... Dr. Paul Brown is Senior Research Scientist in the Laboratory of Central Nervous System ... Address for correspondence: Paul Brown, Building 36, Room 4A-05, ...


http://www.cdc.gov/ncidod/eid/vol7no1/brown.htm


Geographical BSE Risk (GBR) assessments covering 2000-2006

Date : 01.08.2006


http://www.efsa.europa.eu/EFSA/Scientific_Document/GBR_assessments_table_Overview_assessed_countries_2002-2006.pdf


Audit Report

Animal and Plant Health Inspection Service

Bovine Spongiform Encephalopathy (BSE) Surveillance Program - Phase II

and

Food Safety and Inspection Service

Controls Over BSE Sampling, Specified Risk Materials, and Advanced Meat Recovery Products - Phase III

Report No. 50601-10-KC January 2006

Finding 2 Inherent Challenges in Identifying and Testing High-Risk Cattle Still Remain

Our prior report identified a number of inherent problems in identifying and testing high-risk cattle. We reported that the challenges in identifying the universe of high-risk cattle, as well as the need to design procedures to obtain an appropriate representation of samples, was critical to the success of the BSE surveillance program. The surveillance program was designed to target nonambulatory cattle, cattle showing signs of CNS disease (including cattle testing negative for rabies), cattle showing signs not inconsistent with BSE, and dead cattle. Although APHIS designed procedures to ensure FSIS condemned cattle were sampled and made a concerted effort for outreach to obtain targeted samples, industry practices not considered in the design of the surveillance program reduced assurance that targeted animals were tested for BSE.

USDA/OIG-A/50601-10-KC Page 27

observe these animals ante mortem when possible to assure the animals from the target population are ultimately sampled and the clinical signs evaluated.

snip...


http://www.usda.gov/oig/webdocs/50601-10-KC.pdf


GAO-05-51 October 2004 FOOD SAFETY

over 500 customers receiving potentially BSE contaminated beef .....

* GAO-05-51 October 2004 FOOD SAFETY (over 500 customers receiving potentially BSE contaminated beef) - TSS 10/20/04

October 2004 FOOD SAFETY USDA and FDA Need to Better Ensure Prompt and Complete Recalls of Potentially Unsafe Food

snip...

REPORTS

1. Food Safety: USDA and FDA Need to Better Ensure Prompt and Complete Recalls of Potentially Unsafe Food. GAO-05-51, October 7.tss


http://www.gao.gov/new.items/d0551.pdf


Highlights -


http://www.gao.gov/highlights/d0551high.pdf


3. Mad Cow Disease: FDA's Management of the Feed Ban Has Improved, but Oversight Weaknesses Continue to Limit Program Effectiveness. GAO-05-101, Feb. 25.


www.gao.gov/cgi-bin/getrpt?GAO-05-101


Highlights -


www.gao.gov/highlights/d05101high.pdf


SADLY, DEC 2005 SHOWS THAT WE STILL HAVE A SERIOUS PROBLEM WITH BSE/TSE MAD COW DISEASE FEED

GAO

GAO-06-157R FDA Feed Testing Program

October 11, 2005

SNIP...FULL TEXT 29 PAGES ;


http://www.gao.gov/new.items/d06157r.pdf


Mad Cow Disease: An Evaluation of a Small Feed Testing Program FDA Implemented in 2003 With Recommendations for Making the Program a Better Oversight Tool. GAO-06-157R, October 11


http://www.gao.gov/cgi-bin/getrpt?GAO-06-157R


Wednesday, February 27, 2008

BEEF RECALL NATIONWIDE - SCHOOL LUNCH PROGRAM UPDATE


http://downercattle.blogspot.com/2008/02/beef-recall-nationwide-school-lunch.html


Thursday, March 6, 2008

California lists possible recipients of recalled non-ambulatory 'DOWNER' (high potential for TSE) Hallmark beef


http://downercattle.blogspot.com/2008/03/california-lists-possible-recipients-of.html


Thursday, March 6, 2008

House committee subpoenas Hallmark/Westland CEO - i call for an investigation of the investigators


http://downercattle.blogspot.com/2008/03/house-committee-subpoenas.html


Thursday, March 6, 2008

USDA to Hallmark: We want our plaque back

Legal/Regulatory News


http://downercattle.blogspot.com/2008/03/usda-to-hallmark-we-want-our-plaque.html


Thursday, March 6, 2008

To the hard working employees of USDA and their untiring efforts to protect our childrens food supply


http://downercattle.blogspot.com/2008/03/to-hard-working-employees-of-usda-and.html


BEEF RECALL - USA (05) ********************** A ProMED-mail post

ProMED-mail is a program of the International Society for Infectious Diseases


http://www.promedmail.org/pls/otn/f?p=2400:1001:3581618507331539::NO::F2400_P1001_BACK_PAGE,F2400_P1001_PUB_MAIL_ID:1000,71607



THE USDA knows PERFECTLY WELL that no one would get sick right off the bat from mad cow disease. Every parent out there should be demanding answers, not these same lies. THE USDA should follow every single child that consumed any of these products for the rest of there lives. there is no way out of it now. the product is gone, consumed, and these kids, the elderly, and most everybody in between have been exposed. non-ambulatory i.e. DOWNERS are the most likely to have a Transmissible Spongiform Encephalopathy. WE know it's here, we know why the USDA et al shut down the testing, they did not want to document any more. ...TSS

Science 23 November 2001: Vol. 294. no. 5547, pp. 1726 - 1728 DOI: 10.1126/science.1066838

Reports

Estimation of Epidemic Size and Incubation Time Based on Age Characteristics of vCJD in the United Kingdom

Alain-Jacques Valleron,1 Pierre-Yves Boelle,1 Robert Will,2 Jean-Yves Cesbron3

SNIP...

The distribution of the vCJD incubation period that best fits the data within the framework of our model has a mean of 16.7 years, with a standard deviation of 2.6 years. The 95% upper percentile of this distribution is 21.4 years. The 95% confidence interval (CI) of the estimates of the mean and standard deviation is relatively narrow: The 95% CI for the estimate of the mean incubation period is 12.4 to 23.2 years, and the 95% CI of the standard deviation is 0.9 to 8 years (10). The decrease in susceptibility to infection in exposed subjects older than 15 years, as estimated from the parameter , was found to be very sharp: 16% per year of age (CI: 12 to 23%). This means that, under the best fitting hypothesis, an individual aged 20 years in 1981 had 55% less risk of becoming infected than a child aged 15 years (99.9% for an individual aged 70).


http://www.sciencemag.org/


NOW, the price of poker in the USA may be shorter, due to the fact the strain of mad cow disease in the USA is more virulent to humans, thus, the incubation period, for the same titre log of infectivity, via same route and source, might be faster. ...TSS

Communicated by: Terry S. Singeltary Sr.

[In submitting these data, Terry S. Singeltary Sr. draws attention to the steady increase in the "type unknown" category, which, according to their definition, comprises cases in which vCJD could be excluded. The total of 26 cases for the current year (2007) is disturbing, possibly symptomatic of the circulation of novel agents. Characterization of these agents should be given a high priority. - Mod.CP]

[see also:

snip...

************************************************************ Become a ProMED-mail Premium Subscriber at

************************************************************ Visit ProMED-mail's web site at .


http://pro-med.blogspot.com/2007/11/proahedr-prion-disease-update-2007-07.html


SEE STEADY INCREASE IN SPORADIC CJD IN THE USA FROM 1997 TO 2006. SPORADIC CJD CASES TRIPLED, with phenotype of 'UNKNOWN' strain growing. ...


http://www.cjdsurveillance.com/resources-casereport.html


There is a growing number of human CJD cases, and they were presented last week in San Francisco by Luigi Gambatti(?) from his CJD surveillance collection.

He estimates that it may be up to 14 or 15 persons which display selectively SPRPSC and practically no detected RPRPSC proteins.


http://www.fda.gov/ohrms/dockets/ac/06/transcripts/1006-4240t1.htm


http://www.fda.gov/ohrms/dockets/ac/06/transcripts/2006-4240t1.pdf


PLEASE SEE !

P02.35 Molecular Features of the Protease-resistant Prion Protein (PrPres) in H- type BSE

Biacabe, A-G1; Jacobs, JG2; Gavier-Widén, D3; Vulin, J1; Langeveld, JPM2; Baron, TGM1 1AFSSA, France; 2CIDC-Lelystad, Netherlands; 3SVA, Sweden

Western blot analyses of PrPres accumulating in the brain of BSE- infected cattle have demonstrated 3 different molecular phenotypes regarding to the apparent molecular masses and glycoform ratios of PrPres bands. We initially described isolates (H-type BSE) essentially characterized by higher PrPres molecular mass and decreased levels of the diglycosylated PrPres band, in contrast to the classical type of BSE. This type is also distinct from another BSE phenotype named L-type BSE, or also BASE (for Bovine Amyloid Spongiform Encephalopathy), mainly characterized by a low representation of the diglycosylated PrPres band as well as a lower PrPres molecular mass. Retrospective molecular studies in France of all available BSE cases older than 8 years old and of part of the other cases identified since the beginning of the exhaustive surveillance of the disease in 20001 allowed to identify 7 H- type BSE cases, among 594 BSE cases that could be classified as classical, L- or H-type BSE. By Western blot analysis of H-type PrPres, we described a remarkable specific feature with antibodies raised against the C-terminal region of PrP that demonstrated the existence of a more C-terminal cleaved form of PrPres (named PrPres#2 ), in addition to the usual PrPres form (PrPres #1). In the unglycosylated form, PrPres #2 migrates at about 14 kDa, compared to 20 kDa for PrPres #1. The proportion of the PrPres#2 in cattle seems to by higher compared to the PrPres#1. Furthermore another PK–resistant fragment at about 7 kDa was detected by some more N-terminal antibodies and presumed to be the result of cleavages of both N- and C- terminal parts of PrP. These singular features were maintained after transmission of the disease to C57Bl/6 mice. The identification of these two additional PrPres fragments (PrPres #2 and 7kDa band) *** reminds features reported respectively in sporadic Creutzfeldt-Jakob disease and in Gerstmann-Sträussler-Scheinker (GSS) syndrome in humans.

FC5.5.1 BASE Transmitted to Primates and MV2 sCJD Subtype Share PrP27-30 and PrPSc C-terminal Truncated Fragments

Zanusso, G1; Commoy, E2; Fasoli, E3; Fiorini, M3; Lescoutra, N4; Ruchoux, MM4; Casalone, C5; Caramelli, M5; Ferrari, S3; Lasmezas, C6; Deslys, J-P4; Monaco, S3 1University of Verona, of Neurological and Visual Sciences, Italy; 2CEA, IMETI/SEPIA, France; 3University of Verona, Neurological and Visual Sciences, Italy; 4IMETI/SEPIA, France; 5IZSPLVA, Italy; 6The Scripps Research Insitute, USA

The etiology of sporadic Creutzfeldt-Jakob disease (sCJD), the most frequent human prion disease, remains still unknown. The marked disease phenotype heterogeneity observed in sCJD is thought to be influenced by the type of proteinase K- resistant prion protein, or PrPSc (type 1 or type 2 according to the electrophoretic mobility of the unglycosylated backbone), and by the host polymorphic Methionine/Valine (M/V) codon 129 of the PRNP. By using a two-dimensional gel electrophoresis (2D-PAGE) and imunoblotting we previously showed that in sCJD, in addition to the PrPSc type, distinct PrPSc C-terminal truncated fragments (CTFs) correlated with different sCJD subtypes. Based on the combination of CTFs and PrPSc type, we distinguished three PrPSc patterns: (i) the first was observed in sCJD with PrPSc type 1 of all genotypes,;

(ii) the second was found in M/M-2 (cortical form); (iii) the third in amyloidogenic M/V- 2 and V/V-2 subtypes (Zanusso et al., JBC 2004) . Recently, we showed that sCJD subtype M/V-2 shared molecular and pathological features with an atypical form of BSE, named BASE, thus suggesting a potential link between the two conditions. This connection was further confirmed after 2D-PAGE analysis, which showed an identical PrPSc signature, including the biochemical pattern of CTFs. To pursue this issue, we obtained brain homogenates from Cynomolgus macaques intracerebrally inoculated with brain homogenates from BASE. Samples were separated by using a twodimensional electrophoresis (2D-PAGE) followed by immunoblotting. We here show that the PrPSc pattern obtained in infected primates is identical to BASE and sCJD MV-2 subtype. *** These data strongly support the link, or at least a common ancestry, between a sCJD subtype and BASE.

This work was supported by Neuroprion (FOOD-CT-2004-506579)

************************************************** *****

USA MAD COW CASES IN ALABAMA AND TEXAS

***PLEASE NOTE***

USA BASE CASE, (ATYPICAL BSE), AND OR TSE (whatever they are calling it today), please note that both the ALABAMA COW, AND THE TEXAS COW,both were ''H-TYPE'', personal communication Detwiler et al Wednesday, August 22, 2007 11:52 PM. ...TSS




2009 UPDATE ON ALABAMA AND TEXAS MAD COWS 2005 and 2006



http://bse-atypical.blogspot.com/2006/08/bse-atypical-texas-and-alabama-update.html




Wednesday, November 18, 2009

R-CALF: 40 Groups Disagree With USDA's Latest BSE Court Submission


http://bse-atypical.blogspot.com/2009/11/r-calf-40-groups-disagree-with-usdas.html




**************************************************

FC5.5.2 Transmission of Italian BSE and BASE Isolates in Cattle Results into a Typical BSE Phenotype and a Muscle Wasting Disease

Zanusso, G1; Lombardi, G2; Casalone, C3; D’Angelo, A4; Gelmetti, D2; Torcoli, G2; Barbieri, I2; Corona, C3; Fasoli, E1; Farinazzo, A1; Fiorini, M1; Gelati, M1; Iulini, B3; Tagliavini, F5; Ferrari, S1; Monaco, S1; Caramelli, M3; Capucci, L2 1University of Verona, Neurological and Visual Sciences, Italy; 2IZSLER, Italy; 3IZSPLVA, Italy; 4University of Turin, Animal Pathology, Italy; 5Isituto Carlo Besta, Italy

The clinical phenotype of bovine spongiform encephalopathy has been extensively reported in early accounts of the disorder. Following the introduction of statutory active surveillance, almost all BSE cases have been diagnosed on a pathological/molecular basis, in a pre-symptomatic clinical stage. In recent years, the active surveillance system has uncovered atypical BSE cases, which are characterized by distinct conformers of the PrPSc, named high-type (BSE-H) and low-type (BSE-L), whose clinicopathological phenotypes remain unknown. We recently reported two Italian atypical cases with a PrPSc type similar to BSE-L, pathologically characterized by PrP amyloid plaques. Experimental transmission to TgBov mice has recently disclosed that BASE is caused by a distinct prion strain which is extremely virulent. A major limitation of transmission studies to mice is the lack of reliable information on clinical phenotype of BASE in its natural host. In the present study, we experimentally infected Fresian/Holstein and Alpine/Brown cattle with Italian BSE and BASE isolates by i.c. route. BASE infected cattle showed survival times significantly shorter than BSE, a finding more readily evident in Fresian/Holstein, and in keeping with previous observations in TgBov mice. Clinically, BSE-infected cattle developed a disease phenotype highly comparable with that described in field BSE cases and in experimentally challenged cattle. On the contrary, BASE-inoculated cattle developed an amyotrophic disorder accompanied by mental dullness. The molecular and neuropathological profiles, including PrP deposition pattern, closely matched those observed in the original cases. This study further confirms that BASE is caused by a distinct prion isolate and discloses a novel disease phenotype in cattle, closely resembling the phenotype previous reported in scrapie-inoculated cattle *** and in some subtypes of inherited and sporadic Creutzfeldt-Jakob disease.

Oral Abstracts 14

snip...

P04.27

Experimental BSE Infection of Non-human Primates: Efficacy of the Oral Route

Holznagel, E1; Yutzy, B1; Deslys, J-P2; Lasmézas, C2; Pocchiari, M3; Ingrosso, L3; Bierke, P4; Schulz-Schaeffer, W5; Motzkus, D6; Hunsmann, G6; Löwer, J1 1Paul-Ehrlich-Institut, Germany; 2Commissariat à l´Energie Atomique, France; 3Instituto Superiore di Sanità, Italy; 4Swedish Institute for Infectious Disease control, Sweden; 5Georg August University, Germany; 6German Primate Center, Germany

Background:

In 2001, a study was initiated in primates to assess the risk for humans to contract BSE through contaminated food. For this purpose, BSE brain was titrated in cynomolgus monkeys.

Aims:

The primary objective is the determination of the minimal infectious dose (MID50) for oral exposure to BSE in a simian model, and, by in doing this, to assess the risk for humans. Secondly, we aimed at examining the course of the disease to identify possible biomarkers.

Methods:

Groups with six monkeys each were orally dosed with lowering amounts of BSE brain: 16g, 5g, 0.5g, 0.05g, and 0.005g. In a second titration study, animals were intracerebrally (i.c.) dosed (50, 5, 0.5, 0.05, and 0.005 mg).

Results:

In an ongoing study, a considerable number of high-dosed macaques already developed simian vCJD upon oral or intracerebral exposure or are at the onset of the clinical phase. However, there are differences in the clinical course between orally and intracerebrally infected animals that may influence the detection of biomarkers.

Conclusions:

Simian vCJD can be easily triggered in cynomolgus monkeys on the oral route using less than 5 g BSE brain homogenate. The difference in the incubation period between 5 g oral and 5 mg i.c. is only 1 year (5 years versus 4 years). However, there are rapid progressors among orally dosed monkeys that develop simian v CJD as fast as intracerebrally inoculated animals.

The work referenced was performed in partial fulfilment of the study “BSE in primates“ supported by the EU (QLK1-2002-01096).


http://www.prion2007.com/pdf/Prion%20Book%20of%20Abstracts.pdf



Subject: Aspects of the Cerebellar Neuropathology in Nor98

Date: September 26, 2007 at 4:06 pm PST

P03.141

Aspects of the Cerebellar Neuropathology in Nor98

Gavier-Widén, D1; Benestad, SL2; Ottander, L1; Westergren, E1 1National Veterinary Insitute, Sweden; 2National Veterinary Institute, Norway

Nor98 is a prion disease of old sheep and goats. This atypical form of scrapie was first described in Norway in 1998. Several features of Nor98 were shown to be different from classical scrapie including the distribution of disease associated prion protein (PrPd) accumulation in the brain. The cerebellum is generally the most affected brain area in Nor98. The study here presented aimed at adding information on the neuropathology in the cerebellum of Nor98 naturally affected sheep of various genotypes in Sweden and Norway. A panel of histochemical and immunohistochemical (IHC) stainings such as IHC for PrPd, synaptophysin, glial fibrillary acidic protein, amyloid, and cell markers for phagocytic cells were conducted. The type of histological lesions and tissue reactions were evaluated. The types of PrPd deposition were characterized. The cerebellar cortex was regularly affected, even though there was a variation in the severity of the lesions from case to case. Neuropil vacuolation was more marked in the molecular layer, but affected also the granular cell layer. There was a loss of granule cells. Punctate deposition of PrPd was characteristic. It was morphologically and in distribution identical with that of synaptophysin, suggesting that PrPd accumulates in the synaptic structures. PrPd was also observed in the granule cell layer and in the white matter. *** The pathology features of Nor98 in the cerebellum of the affected sheep showed similarities with those of sporadic Creutzfeldt-Jakob disease in humans.

http://www.prion2007.com/pdf/Prion%20Book%20of%20Abstracts.pdf


full text ;

ATYPICAL NOR-98 SCRAPIE LOCATION UPDATE ON 5 DOCUMENTED CASES THIS YEAR ;

The flocks of origin are WY, CO, CA, IN, and MN.

personal communication USDA et al. ...TSS

http://nor-98.blogspot.com/



never forget what deepthroat told me in 2000-2001. this person was high official in USDA. ...tss


============================================================


The most frightening thing I have read all day is the report of Gambetti's finding of a new strain of sporadic cjd in young people.........Dear God, what in the name of all that is holy is that!!! If the US has different strains of scrapie.....why????than the UK...then would the same mechanisms that make different strains of scrapie here make different strains of BSE...if the patterns are different in sheep and mice for scrapie.....could not the BSE be different in the cattle, in the mink, in the humans.......I really think the slides or tissues and everything from these young people with the new strain of sporadic cjd should be put up to be analyzed by many, many experts in cjd........bse.....scrapie Scrape the damn slide and put it into mice.....wait.....chop up the mouse brain and and spinal cord........put into some more mice.....dammit amplify the thing and start the damned research.....This is NOT rocket science...we need to use what we know and get off our butts and move....the whining about how long everything takes.....well it takes a whole lot longer if you whine for a year and then start the research!!! Not sure where I read this but it was a recent press release or something like that: I thought I would fall out of my chair when I read about how there was no worry about infectivity from a histopath slide or tissues because they are preserved in formic acid, or formalin or formaldehyde.....for God's sake........ Ask any pathologist in the UK what the brain tissues in the formalin looks like after a year.......it is a big fat sponge...the agent continues to eat the brain ......you can't make slides anymore because the agent has never stopped........and the old slides that are stained with Hemolysin and Eosin......they get holier and holier and degenerate and continue...what you looked at 6 months ago is not there........Gambetti better be photographing every damned thing he is looking at.....

Okay, you need to know. You don't need to pass it on as nothing will come of it and there is not a damned thing anyone can do about it. Don't even hint at it as it will be denied and laughed at.......... USDA is gonna do as little as possible until there is actually a human case in the USA of the nvcjd........if you want to move this thing along and shake the earth....then we gotta get the victims families to make sure whoever is doing the autopsy is credible, trustworthy, and a saint with the courage of Joan of Arc........I am not kidding!!!! so, unless we get a human death from EXACTLY the same form with EXACTLY the same histopath lesions as seen in the UK nvcjd........forget any action........it is ALL gonna be sporadic!!!

And, if there is a case.......there is gonna be every effort to link it to international travel, international food, etc. etc. etc. etc. etc. They will go so far as to find out if a sex partner had ever traveled to the UK/europe, etc. etc. .... It is gonna be a long, lonely, dangerous twisted journey to the truth. They have all the cards, all the money, and are willing to threaten and carry out those threats....and this may be their biggest downfall...

Thanks as always for your help. (Recently had a very startling revelation from a rather senior person in government here..........knocked me out of my chair........you must keep pushing. If I was a power person....I would be demanding that there be a least a million bovine tested as soon as possible and agressively seeking this disease. The big players are coming out of the woodwork as there is money to be made!!! In short: "FIRE AT WILL"!!! for the very dumb....who's "will"! "Will be the burden to bare if there is any coverup!"

again it was said years ago and it should be taken seriously....BSE will NEVER be found in the US! As for the BSE conference call...I think you did a great service to freedom of information and making some people feign integrity...I find it scary to see that most of the "experts" are employed by the federal government or are supported on the "teat" of federal funds. A scary picture! I hope there is a confidential panel organized by the new government to really investigate this thing.

You need to watch your back........but keep picking at them.......like a buzzard to the bone...you just may get to the truth!!! (You probably have more support than you know. Too many people are afraid to show you or let anyone else know. I have heard a few things myself... you ask the questions that everyone else is too afraid to ask.)


================================================================


2008

considering the BASE strains of atypical BSE are more virulent to humans, considering the BASE resembles that of the some subtypes of sporadic CJD and GSS, considering all this, IF i were the USDA et al, i would be more worried about getting all the potentially tainted mad cow blood back, than the damn plaque. ..

P.S. Gambetti et al recently said that the BASE atypical BSE are more virulent to humans. other scientists have said the same thing. however Gambetti claims it does not resemble sCJD, but every other scientist says it does. you be the judge.........

Evaluation of the Human Transmission Risk of an Atypical Bovine Spongiform Encephalopathy Prion Strain

J. Virol. doi:10.1128/JVI.02561-07

Minimal brain spongiosis and long incubation time are observed in the BASE-infected Tg mice. These results suggest that, in humans, BASE is a more virulent BSE strain and likely lymphotropic.


http://jvi.asm.org/cgi/content/abstract/JVI.02561-07v1?papetoc


for those interested, further into this study, it gets very interesting ;


http://cjdmadcowbaseoct2007.blogspot.com/2008/02/evaluation-of-human-transmission-risk.html


CJD QUESTIONNAIRE


http://cjdquestionnaire.blogspot.com/


[Docket No. FSIS-2006-0011] FSIS Harvard Risk Assessment of Bovine Spongiform Encephalopathy (BSE)


http://www.fsis.usda.gov/OPPDE/Comments/2006-0011/2006-0011-1.pdf


suppressed peer review of Harvard study October 31, 2002


http://www.fsis.usda.gov/oa/topics/BSE_Peer_Review.pdf


APHIS-2006-0041-0006 TSE advisory committee for the meeting December 15, 2006


http://www.regulations.gov/fdmspublic/ContentViewer?objectId=09000064801f3413&disposition=attachment&contentType=msw8


Attachment to Singeltary comment

January 28, 2007

Greetings APHIS,

I would kindly like to submit the following to ;

BSE; MRR; IMPORTATION OF LIVE BOVINES AND PRODUCTS DERIVED FROM BOVINES [Docket No. APHIS-2006-0041] RIN 0579-AC01

[Federal Register: January 9, 2007 (Volume 72, Number 5)] [Proposed Rules] [Page 1101-1129] From the Federal Register Online via GPO Access [wais.access.gpo.gov] [DOCID:fr09ja07-21]


http://www.regulations.gov/fdmspublic/component/main?main=DocumentDetail&o=09000064801f8152


BSE; MRR; IMPORTATION OF LIVE BOVINES AND PRODUCTS DERIVED FROM BOVINES [Docket No. APHIS-2006-0041] RIN 0579-AC01 Date: January 9, 2007 at 9:08 am PST


http://www.regulations.gov/fdmspublic/component/main?main=DocumentDetail&o=09000064801f3412


Web posted Friday, January 23, 1998 5:49 a.m. CT

TSS

Witness testifies some ill cattle sent to rendering plant

By CHIP CHANDLER Globe-News Staff Writer

snip...

Mike Engler -- son of Paul Engler, the original plaintiff and owner of Cactus Feeders Inc. -- agreed that more than 10 cows with some sort of central nervous system disorder were sent to Hereford By-Products.

The younger Engler, who has a doctorate in biochemistry from Johns Hopkins University, was the only witness jurors heard Thursday in the Oprah Winfrey defamation trial. His testimony will resume this morning.

According to a U.S. Department of Agriculture report from which Winfrey attorney Charles Babcock quoted, encephalitis caused by unknown reasons could be a warning sign for bovine spongiform encephalopathy, or mad cow disease.

Encephalitis was indicated on the death certificates -- or ``dead slips'' -- of three Cactus Feeders cows discussed in court. The slips then were stamped, ``Picked up by your local used cattle dealer'' before the carcasses were taken to the rendering plant.

snip...


http://www.amarillonet.com/


FOR IMMEDIATE RELEASE Statement May 4, 2004 Media Inquiries: 301-827-6242 Consumer Inquiries: 888-INFO-FDA

Statement on Texas Cow With Central Nervous System Symptoms On Friday, April 30 th , the Food and Drug Administration learned that a cow with central nervous system symptoms had been killed and shipped to a processor for rendering into animal protein for use in animal feed.

FDA, which is responsible for the safety of animal feed, immediately began an investigation. On Friday and throughout the weekend, FDA investigators inspected the slaughterhouse, the rendering facility, the farm where the animal came from, and the processor that initially received the cow from the slaughterhouse.

FDA's investigation showed that the animal in question had already been rendered into "meat and bone meal" (a type of protein animal feed). Over the weekend FDA was able to track down all the implicated material. That material is being held by the firm, which is cooperating fully with FDA.

Cattle with central nervous system symptoms are of particular interest because cattle with bovine spongiform encephalopathy or BSE, also known as "mad cow disease," can exhibit such symptoms. In this case, there is no way now to test for BSE. But even if the cow had BSE, FDA's animal feed rule would prohibit the feeding of its rendered protein to other ruminant animals (e.g., cows, goats, sheep, bison).

FDA is sending a letter to the firm summarizing its findings and informing the firm that FDA will not object to use of this material in swine feed only. If it is not used in swine feed, this material will be destroyed. Pigs have been shown not to be susceptible to BSE. If the firm agrees to use the material for swine feed only, FDA will track the material all the way through the supply chain from the processor to the farm to ensure that the feed is properly monitored and used only as feed for pigs.

To protect the U.S. against BSE, FDA works to keep certain mammalian protein out of animal feed for cattle and other ruminant animals. FDA established its animal feed rule in 1997 after the BSE epidemic in the U.K. showed that the disease spreads by feeding infected ruminant protein to cattle.

Under the current regulation, the material from this Texas cow is not allowed in feed for cattle or other ruminant animals. FDA's action specifying that the material go only into swine feed means also that it will not be fed to poultry.

FDA is committed to protecting the U.S. from BSE and collaborates closely with the U.S. Department of Agriculture on all BSE issues. The animal feed rule provides crucial protection against the spread of BSE, but it is only one of several such firewalls. FDA will soon be improving the animal feed rule, to make this strong system even stronger.

####


http://www.fda.gov/bbs/topics/news/2004/NEW01061.html



Beef - Westland/Hallmark Recall OF BEEF WITH DEADSTOCK DOWNER COWS, THE MOST HIGH RISK CATTLE FOR BSE/TSE AKA MAD COW DISEASE


Additional Products Listing 5-20-08



http://www.cdph.ca.gov/pubsforms/Documents/fdb%20eru%20Hmrk%20Addl%20Prod052008.pdf




http://www.cdph.ca.gov/HEALTHINFO/Pages/FDB%20Beef-WestlandHallmarkRecall.aspx



TOTAL DISTRIBUTION LIST



http://www.cdph.ca.gov/pubsforms/Documents/fdb%20eru%20Hmrk%20All%20Dist042008.pdf



ADDITIONAL PRODUCTS CONTAINING RECALLED BEEF



http://www.cdph.ca.gov/pubsforms/Documents/fdb%20eru%20Hmrk%20Addl%20Prod052008.pdf




SEE FULL LIST OF ALL RECALLED SUSPECT DEAD STOCK DOWNER COW PRODUCTS HERE ;



http://www.cdph.ca.gov/HEALTHINFO/Pages/FDB%20Beef-WestlandHallmarkRecall.aspx




>>>In the papers, the government alleges the meatpacking plant slaughtered and processed downer cows for nearly four years — from January 2004 to September 2007 — <<<



>> 95%) downer or dead dairy cattle and a few horses. Sheep had never been fed.





We believe that these findings may indicate the presence of a previously unrecognized scrapie-like disease in cattle and wish to alert dairy practitioners to this possibility.

snip...

PROCEEDINGS OF THE SEVENTH ANNUAL WESTERN CONFERENCE FOR FOOD ANIMAL VETERINARY MEDICINE, University of Arizona, March 17-19, 1986




http://web.archive.org/web/20030331063559/http://www.bseinquiry.gov.uk/files/mb/m09a/tab01.pdf






http://web.archive.org/web/20030516051623/http://www.bseinquiry.gov.uk/files/mb/m09/tab05.pdf




IN CONFIDENCE

PERCEPTIONS OF UNCONVENTIONAL SLOW VIRUS DISEASES OF ANIMALS IN THE USA


http://collections.europarchive.org/tna/20080102193705/http://www.bseinquiry.gov.uk/files/mb/m11b/tab01.pdf






TSS